Systems analysis of eleven rodent disease models reveals an inflammatome signature and key drivers
Systems analysis of eleven rodent disease models reveals an inflammatome signature and key drivers
About this item
Full title
Author / Creator
Wang, I‐Ming , Zhang, Bin , Yang, Xia , Zhu, Jun , Stepaniants, Serguei , Zhang, Chunsheng , Meng, Qingying , Peters, Mette , He, Yudong , Ni, Chester , Slipetz, Deborah , Crackower, Michael A , Houshyar, Hani , Tan, Christopher M , Asante‐Appiah, Ernest , O'Neill, Gary , Jane Luo, Mingjuan , Thieringer, Rolf , Yuan, Jeffrey , Chiu, Chi‐Sung , Yee Lum, Pek , Lamb, John , Boie, Yves , Wilkinson, Hilary A , Schadt, Eric E , Dai, Hongyue and Roberts, Christopher
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Common inflammatome gene signatures as well as disease‐specific signatures were identified by analyzing 12 expression profiling data sets derived from 9 different tissues isolated from 11 rodent inflammatory disease models. The inflammatome signature significantly overlaps with known drug targets and co‐expressed gene modules linked to metabolic di...
Alternative Titles
Full title
Systems analysis of eleven rodent disease models reveals an inflammatome signature and key drivers
Authors, Artists and Contributors
Author / Creator
Zhang, Bin
Yang, Xia
Zhu, Jun
Stepaniants, Serguei
Zhang, Chunsheng
Meng, Qingying
Peters, Mette
He, Yudong
Ni, Chester
Slipetz, Deborah
Crackower, Michael A
Houshyar, Hani
Tan, Christopher M
Asante‐Appiah, Ernest
O'Neill, Gary
Jane Luo, Mingjuan
Thieringer, Rolf
Yuan, Jeffrey
Chiu, Chi‐Sung
Yee Lum, Pek
Lamb, John
Boie, Yves
Wilkinson, Hilary A
Schadt, Eric E
Dai, Hongyue
Roberts, Christopher
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_7f8736e3694946c78134d40fac8a24ec
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7f8736e3694946c78134d40fac8a24ec
Other Identifiers
ISSN
1744-4292
E-ISSN
1744-4292
DOI
10.1038/msb.2012.24
