Transfer learning enables prediction of CYP2D6 haplotype function
Transfer learning enables prediction of CYP2D6 haplotype function
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Cytochrome P450 2D6 (
CYP2D6
) is a highly polymorphic gene whose protein product metabolizes more than 20% of clinically used drugs. Genetic variations in
CYP2D6
are responsible for interindividual heterogeneity in drug response that can lead to drug toxicity and ineffective treatment, making
CYP2D6
one of the most important phar...
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Full title
Transfer learning enables prediction of CYP2D6 haplotype function
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TN_cdi_doaj_primary_oai_doaj_org_article_7fff972297404355b40a56134eab5609
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7fff972297404355b40a56134eab5609
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ISSN
1553-7358,1553-734X
E-ISSN
1553-7358
DOI
10.1371/journal.pcbi.1008399