The Mitochondrial Unfolded Protein Response: A Hinge Between Healthy and Pathological Aging
The Mitochondrial Unfolded Protein Response: A Hinge Between Healthy and Pathological Aging
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Publisher
Lausanne: Frontiers Research Foundation
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Language
English
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Publisher
Lausanne: Frontiers Research Foundation
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Contents
Aging is the time-dependent functional decline that increases the vulnerability to different forms of stress, constituting the major risk factor for the development of neurodegenerative diseases. Dysfunctional mitochondria significantly contribute to aging phenotypes, accumulating particularly in post-mitotic cells, including neurons. To cope with...
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Full title
The Mitochondrial Unfolded Protein Response: A Hinge Between Healthy and Pathological Aging
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Author / Creator
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TN_cdi_doaj_primary_oai_doaj_org_article_802c4ef399104563922226afd19aef46
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_802c4ef399104563922226afd19aef46
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ISSN
1663-4365
E-ISSN
1663-4365
DOI
10.3389/fnagi.2020.581849
