Differential effects on KCC2 expression and spasticity of ALS and traumatic injuries to motoneurons
Differential effects on KCC2 expression and spasticity of ALS and traumatic injuries to motoneurons
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Publisher
Switzerland: Frontiers Research Foundation
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Language
English
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Publisher
Switzerland: Frontiers Research Foundation
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Scope and Contents
Contents
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease manifested by progressive muscle atrophy and paralysis due to the loss of upper and lower motoneurons (MN). Spasticity appears in ALS patients leading to further disabling consequences. Loss of the inhibitory tone induced by downregulation of the potassium chloride cotransporter 2 (...
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Full title
Differential effects on KCC2 expression and spasticity of ALS and traumatic injuries to motoneurons
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TN_cdi_doaj_primary_oai_doaj_org_article_80c7ec343a534549ae4c4044b4674518
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_80c7ec343a534549ae4c4044b4674518
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ISSN
1662-5102
E-ISSN
1662-5102
DOI
10.3389/fncel.2014.00007
