Precise base editing for the in vivo study of developmental signaling and human pathologies in zebra...
Precise base editing for the in vivo study of developmental signaling and human pathologies in zebrafish
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Publisher
England: eLife Science Publications, Ltd
Journal title
Language
English
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Publisher
England: eLife Science Publications, Ltd
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Contents
While zebrafish is emerging as a new model system to study human diseases, an efficient methodology to generate precise point mutations at high efficiency is still lacking. Here we show that base editors can generate C-to-T point mutations with high efficiencies without other unwanted on-target mutations. In addition, we established a new editor va...
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Full title
Precise base editing for the in vivo study of developmental signaling and human pathologies in zebrafish
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TN_cdi_doaj_primary_oai_doaj_org_article_813cd8e9727044e4873ab8af888f118c
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_813cd8e9727044e4873ab8af888f118c
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.65552
