Convergent TP53 loss and evolvability in cancer
Convergent TP53 loss and evolvability in cancer
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Publisher
England: BioMed Central Ltd
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Language
English
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England: BioMed Central Ltd
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Contents
Cancer cell populations evolve by a stepwise process involving natural selection of the fittest variants within a tissue ecosystem context and as modified by therapy. Genomic scrutiny of patient samples reveals an extraordinary diversity of mutational profiles both between patients with similar cancers and within the cancer cell population of indiv...
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Full title
Convergent TP53 loss and evolvability in cancer
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TN_cdi_doaj_primary_oai_doaj_org_article_81b561c838494a0a84275f22be7b52e4
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_81b561c838494a0a84275f22be7b52e4
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ISSN
2730-7182
E-ISSN
2730-7182
DOI
10.1186/s12862-023-02146-6