Amyloid-β aggregates activate peripheral monocytes in mild cognitive impairment
Amyloid-β aggregates activate peripheral monocytes in mild cognitive impairment
About this item
Full title
Author / Creator
Juul-Madsen, Kristian , Parbo, Peter , Ismail, Rola , Ovesen, Peter L. , Schmidt, Vanessa , Madsen, Lasse S. , Thyrsted, Jacob , Gierl, Sarah , Breum, Mihaela , Larsen, Agnete , Andersen, Morten N. , Romero-Ramos, Marina , Holm, Christian K. , Andersen, Gregers R. , Zhao, Huaying , Schuck, Peter , Nygaard, Jens V. , Sutherland, Duncan S. , Eskildsen, Simon F. , Willnow, Thomas E. , Brooks, David J. and Vorup-Jensen, Thomas
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The peripheral immune system is important in neurodegenerative diseases, both in protecting and inflaming the brain, but the underlying mechanisms remain elusive. Alzheimer’s Disease is commonly preceded by a prodromal period. Here, we report the presence of large Aβ aggregates in plasma from patients with mild cognitive impairment (
n
= 38)...
Alternative Titles
Full title
Amyloid-β aggregates activate peripheral monocytes in mild cognitive impairment
Authors, Artists and Contributors
Author / Creator
Parbo, Peter
Ismail, Rola
Ovesen, Peter L.
Schmidt, Vanessa
Madsen, Lasse S.
Thyrsted, Jacob
Gierl, Sarah
Breum, Mihaela
Larsen, Agnete
Andersen, Morten N.
Romero-Ramos, Marina
Holm, Christian K.
Andersen, Gregers R.
Zhao, Huaying
Schuck, Peter
Nygaard, Jens V.
Sutherland, Duncan S.
Eskildsen, Simon F.
Willnow, Thomas E.
Brooks, David J.
Vorup-Jensen, Thomas
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_81c39ad41509420b82e48e637c1da445
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_81c39ad41509420b82e48e637c1da445
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-45627-y