Prognostic significance of BRAF and NRAS mutations in melanoma: a German study from routine care
Prognostic significance of BRAF and NRAS mutations in melanoma: a German study from routine care
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Hotspot mutations of the oncogenes BRAF and NRAS are the most common genetic alterations in cutaneous melanoma. Specific inhibitors of BRAF and MEK have shown significant survival benefits in large phase III trials. However, the prognostic significance of BRAF and NRAS mutations outside of clinical trials remains unclear.
The mutational status o...
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Full title
Prognostic significance of BRAF and NRAS mutations in melanoma: a German study from routine care
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TN_cdi_doaj_primary_oai_doaj_org_article_8209b72165cd492a99ec754cc11007a9
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8209b72165cd492a99ec754cc11007a9
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ISSN
1471-2407
E-ISSN
1471-2407
DOI
10.1186/s12885-017-3529-5
