Amiloride ameliorates muscle wasting in cancer cachexia through inhibiting tumor-derived exosome rel...
Amiloride ameliorates muscle wasting in cancer cachexia through inhibiting tumor-derived exosome release
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Author / Creator
Zhou, Lin , Zhang, Tong , Shao, Wei , Lu, Ruohan , Wang, Lin , Liu, Haisheng , Jiang, Bin , Li, Shiqin , Zhuo, Huiqin , Wang, Suheng , Li, Qinxi , Huang, Caihua and Lin, Donghai
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publication information
Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Cancer cachexia (CAC) reduces patient survival and quality of life. Developments of efficient therapeutic strategies are required for the CAC treatments. This long-term process could be shortened by the drug-repositioning approach which exploits old drugs approved for non-cachexia disease. Amiloride, a diuretic drug, is clinically used for treatmen...
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Full title
Amiloride ameliorates muscle wasting in cancer cachexia through inhibiting tumor-derived exosome release
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_8248392b8ab649598821f23895d2eb40
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8248392b8ab649598821f23895d2eb40
Other Identifiers
ISSN
2044-5040
E-ISSN
2044-5040
DOI
10.1186/s13395-021-00274-5