Production of individualized V gene databases reveals high levels of immunoglobulin genetic diversit...
Production of individualized V gene databases reveals high levels of immunoglobulin genetic diversity
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Comprehensive knowledge of immunoglobulin genetics is required to advance our understanding of B cell biology. Validated immunoglobulin variable (V) gene databases are close to completion only for human and mouse. We present a novel computational approach, IgDiscover, that identifies germline V genes from expressed repertoires to a specificity of 1...
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Production of individualized V gene databases reveals high levels of immunoglobulin genetic diversity
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TN_cdi_doaj_primary_oai_doaj_org_article_8347676fcb7f429d81b27ddb94c2bdb4
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8347676fcb7f429d81b27ddb94c2bdb4
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms13642
