Deletion of 3p13-14 locus spanning FOXP1 to SHQ1 cooperates with PTEN loss in prostate oncogenesis
Deletion of 3p13-14 locus spanning FOXP1 to SHQ1 cooperates with PTEN loss in prostate oncogenesis
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
A multigenic locus at 3p13-14, spanning
FOXP1
to
SHQ1
, is commonly deleted in prostate cancer and lost broadly in a range of cancers but has unknown significance to oncogenesis or prognosis. Here, we report that
FOXP1-SHQ1
deletion cooperates with
PTEN
loss to accelerate prostate oncogenesis and that loss of component genes...
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Full title
Deletion of 3p13-14 locus spanning FOXP1 to SHQ1 cooperates with PTEN loss in prostate oncogenesis
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TN_cdi_doaj_primary_oai_doaj_org_article_836ceacd80084e6394c47fe1007f64e2
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_836ceacd80084e6394c47fe1007f64e2
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-017-01198-9
