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ArticlesPeer ReviewedFull Text
Constitutively active androgen receptor splice variants expressed in castration-resistant prostate cancer require full-length androgen receptor
Author / Creator:Watson, Philip A. ; Chen, Yinan F. ; Balbas, Minna D. ; Wongvipat, John ; Socci, Nicholas D. ; Viale, Agnes ; Kim, Kwanghee ; Sawyers, Charles L.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2010-09, Vol.107 (39), p.16759-16765
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ETS factors reprogram the androgen receptor cistrome and prime prostate tumorigenesis in response to PTEN loss
Author / Creator:Chen, Yu ; Chi, Ping ; Rockowitz, Shira ; Iaquinta, Phillip J ; Shamu, Tambudzai ; Shukla, Shipra ; Gao, Dong ; Sirota, Inna ; Carver, Brett S ; Wongvipat, John ; Scher, Howard I ; Zheng, Deyou ; Sawyers, Charles L
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2013-08, Vol.19 (8), p.1023-1029
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Noninvasive measurement of androgen receptor signaling with a positron-emitting radiopharmaceutical that targets prostate-specific membrane antigen
Author / Creator:Evans, Michael J ; Smith-Jones, Peter M ; Wongvipat, John ; Navarro, Vincent ; Kim, Sae ; Bander, Neil H ; Larson, Steven M ; Sawyers, Charles L
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2011-06, Vol.108 (23), p.9578-9582
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Regulation of the glucocorticoid receptor via a BET-dependent enhancer drives antiandrogen resistance in prostate cancer
Author / Creator:Shah, Neel ; Wang, Ping ; Wongvipat, John ; Karthaus, Wouter R ; Abida, Wassim ; Armenia, Joshua ; Rockowitz, Shira ; Drier, Yotam ; Bernstein, Bradley E ; Long, Henry W ; Freedman, Matthew L ; Arora, Vivek K ; Zheng, Deyou ; Sawyers, Charles L
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2017-09, Vol.6
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Development of a Second-Generation Antiandrogen for Treatment of Advanced Prostate Cancer
Author / Creator:Tran, Chris ; Ouk, Samedy ; Clegg, Nicola J ; Chen, Yu ; Watson, Philip A ; Arora, Vivek ; Wongvipat, John ; Smith-Jones, Peter M ; Yoo, Dongwon ; Kwon, Andrew ; Wasielewska, Teresa ; Welsbie, Derek ; Chen, Charlie Degui ; Higano, Celestia S ; Beer, Tomasz M ; Hung, David T ; Scher, Howard I ; Jung, Michael E ; Sawyers, Charles L
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2009-05, Vol.324 (5928), p.787-790
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Overcoming mutation-based resistance to antiandrogens with rational drug design
Author / Creator:Balbas, Minna D ; Evans, Michael J ; Hosfield, David J ; Wongvipat, John ; Arora, Vivek K ; Watson, Philip A ; Chen, Yu ; Greene, Geoffrey L ; Shen, Yang ; Sawyers, Charles L
Publisher:England: eLife Sciences Publications Ltd
Journal title:eLife, 2013-04, Vol.2, p.e00499
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Deletion of 3p13-14 locus spanning FOXP1 to SHQ1 cooperates with PTEN loss in prostate oncogenesis
Author / Creator:Hieronymus, Haley ; Iaquinta, Phillip J. ; Wongvipat, John ; Gopalan, Anuradha ; Murali, Rajmohan ; Mao, Ninghui ; Carver, Brett S. ; Sawyers, Charles L.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-10, Vol.8 (1), p.1081-10, Article 1081
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MAGI-2 scaffold protein is critical for kidney barrier function
Author / Creator:Balbas, Minna D. ; Burgess, Michael R. ; Murali, Rajmohan ; Wongvipat, John ; Skaggs, Brian J. ; Mundel, Peter ; Weins, Astrid ; Sawyers, Charles L.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2014-10, Vol.111 (41), p.14876-14881
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GREB1 amplifies androgen receptor output in human prostate cancer and contributes to antiandrogen resistance
Author / Creator:Lee, Eugine ; Wongvipat, John ; Choi, Danielle ; Wang, Ping ; Lee, Young Sun ; Zheng, Deyou ; Watson, Philip A ; Gopalan, Anuradha ; Sawyers, Charles L
Publisher:England: eLife Sciences Publications Ltd
Journal title:eLife, 2019-01, Vol.8
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MYC Cooperates with AKT in Prostate Tumorigenesis and Alters Sensitivity to mTOR Inhibitors
Author / Creator:Clegg, Nicola J. ; Couto, Suzana S. ; Wongvipat, John ; Hieronymus, Haley ; Carver, Brett S. ; Taylor, Barry S. ; Ellwood-Yen, Katharine ; Gerald, William L. ; Sander, Chris ; Sawyers, Charles L.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2011-03, Vol.6 (3), p.e17449-e17449
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SOX2 promotes lineage plasticity and antiandrogen resistance in TP53- and RB1-deficient prostate cancer
Author / Creator:Mu, Ping ; Zhang, Zeda ; Benelli, Matteo ; Karthaus, Wouter R. ; Hoover, Elizabeth ; Chen, Chi-Chao ; Wongvipat, John ; Ku, Sheng-Yu ; Gao, Dong ; Cao, Zhen ; Shah, Neel ; Adams, Elizabeth J. ; Abida, Wassim ; Watson, Philip A. ; Prandi, Davide ; Huang, Chun-Hao ; de Stanchina, Elisa ; Lowe, Scott W. ; Ellis, Leigh ; Beltran, Himisha ; Rubin, Mark A. ; Goodrich, David W. ; Demichelis, Francesca ; Sawyers, Charles L.
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2017-01, Vol.355 (6320), p.84-88
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ETV1 is a lineage survival factor that cooperates with KIT in gastrointestinal stromal tumours
Author / Creator:Chi, Ping ; Chen, Yu ; Zhang, Lei ; Guo, Xingyi ; Wongvipat, John ; Shamu, Tambudzai ; Fletcher, Jonathan A. ; Dewell, Scott ; Maki, Robert G. ; Zheng, Deyou ; Antonescu, Cristina R. ; Allis, C. David ; Sawyers, Charles L.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2010-10, Vol.467 (7317), p.849-853
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ArticlesPeer ReviewedFull Text
Cooperativity of TMPRSS2-ERG with PI3-kinase pathway activation in prostate oncogenesis
Author / Creator:King, Jennifer C ; Xu, Jin ; Wongvipat, John ; Hieronymus, Haley ; Carver, Brett S ; Leung, David H ; Taylor, Barry S ; Sander, Chris ; Cardiff, Robert D ; Couto, Suzana S ; Gerald, William L ; Sawyers, Charles L
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2009-05, Vol.41 (5), p.524-526
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Annotating MYC status with [.sup.89]Zr-transferrin imaging
Author / Creator:Holland, Jason P ; Evans, Michael J ; Rice, Samuel L ; Wongvipat, John ; Sawyers, Charles L ; Lewis, Jason S
Publisher:Nature Publishing Group
Journal title:Nature medicine, 2012-10, Vol.18 (10), p.1586
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ERF mutations reveal a balance of ETS factors controlling prostate oncogenesis
Author / Creator:Bose, Rohit ; Karthaus, Wouter R. ; Armenia, Joshua ; Abida, Wassim ; Iaquinta, Phillip J. ; Zhang, Zeda ; Wongvipat, John ; Wasmuth, Elizabeth V. ; Shah, Neel ; Sullivan, Patrick S. ; Doran, Michael G. ; Wang, Ping ; Patruno, Anna ; Zhao, Yilin ; Zheng, Deyou ; Schultz, Nikolaus ; Sawyers, Charles L.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2017-06, Vol.546 (7660), p.671-675
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ArticlesPeer ReviewedFull Text
Annotating MYC status with 89Zr-transferrin imaging
Author / Creator:Holland, Jason P ; Evans, Michael J ; Rice, Samuel L ; Wongvipat, John ; Sawyers, Charles L ; Lewis, Jason S
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2012-10, Vol.18 (10), p.1586-1591
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COP1/DET1/ETS axis regulates ERK transcriptome and sensitivity to MAPK inhibitors
Author / Creator:Xie, Yuanyuan ; Cao, Zhen ; Wong, Elissa W.P. ; Guan, Youxin ; Ma, Wenfu ; Zhang, Jenny Q. ; Walczak, Edward G. ; Murphy, Devan ; Ran, Leili ; Sirota, Inna ; Wang, Shangqian ; Shukla, Shipra ; Gao, Dong ; Knott, Simon R.V. ; Chang, Kenneth ; Leu, Justin ; Wongvipat, John ; Antonescu, Cristina R. ; Hannon, Gregory ; Chi, Ping ; Chen, Yu
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2018-04, Vol.128 (4), p.1442-1457
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ArticlesPeer ReviewedFull Text
Annotating MYC oncogene status with 89Zr-transferrin imaging
Author / Creator:Holland, Jason P. ; Evans, Michael J. ; Rice, Samuel L. ; Wongvipat, John ; Sawyers, Charles L. ; Lewis, Jason S.
Journal title:Nature medicine, 2012-09, Vol.18 (10), p.1586-1591
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ETV1 is a lineage-specific survival factor in GIST and cooperates with KIT in oncogenesis
Author / Creator:Chi, Ping ; Chen, Yu ; Zhang, Lei ; Guo, Xingyi ; Wongvipat, John ; Shamu, Tambudzai ; Fletcher, Jonathan A. ; Dewell, Scott ; Maki, Robert G. ; Zheng, Deyou ; Antonescu, Cristina R. ; Allis, C. David ; Sawyers, Charles L.
Journal title:Nature (London), 2010-10, Vol.467 (7317), p.849-853
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ArticlesFull Text
GREB1 amplifies androgen receptor output in prostate cancer and contributes to antiandrogen resistance
Author / Creator:Sawyers, Charles L ; Lee, Eugine ; Wongvipat, John ; Choi, Danielle ; Wang, Ping ; Zheng, Deyou ; Watson, Philip A ; Gopalan, Anuradha
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2018-10
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Constitutively active androgen receptor splice variants expressed in castration-resistant prostate cancer require full-length androgen receptor

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ETS factors reprogram the androgen receptor cistrome and prime prostate tumorigenesis in response to PTEN loss

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Noninvasive measurement of androgen receptor signaling with a positron-emitting radiopharmaceutical that targets prostate-specific membrane antigen

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Regulation of the glucocorticoid receptor via a BET-dependent enhancer drives antiandrogen resistance in prostate cancer

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Development of a Second-Generation Antiandrogen for Treatment of Advanced Prostate Cancer

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Overcoming mutation-based resistance to antiandrogens with rational drug design

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Deletion of 3p13-14 locus spanning FOXP1 to SHQ1 cooperates with PTEN loss in prostate oncogenesis

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MAGI-2 scaffold protein is critical for kidney barrier function

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GREB1 amplifies androgen receptor output in human prostate cancer and contributes to antiandrogen resistance

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MYC Cooperates with AKT in Prostate Tumorigenesis and Alters Sensitivity to mTOR Inhibitors

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SOX2 promotes lineage plasticity and antiandrogen resistance in TP53- and RB1-deficient prostate cancer

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ETV1 is a lineage survival factor that cooperates with KIT in gastrointestinal stromal tumours

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Cooperativity of TMPRSS2-ERG with PI3-kinase pathway activation in prostate oncogenesis

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Annotating MYC status with [.sup.89]Zr-transferrin imaging

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ERF mutations reveal a balance of ETS factors controlling prostate oncogenesis

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Annotating MYC status with 89Zr-transferrin imaging

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COP1/DET1/ETS axis regulates ERK transcriptome and sensitivity to MAPK inhibitors

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Annotating MYC oncogene status with 89Zr-transferrin imaging

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ETV1 is a lineage-specific survival factor in GIST and cooperates with KIT in oncogenesis

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GREB1 amplifies androgen receptor output in prostate cancer and contributes to antiandrogen resistance

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