Single cell transcriptome analysis of the THY-Tau22 mouse model of Alzheimer’s disease reveals sex-d...
Single cell transcriptome analysis of the THY-Tau22 mouse model of Alzheimer’s disease reveals sex-dependent dysregulations
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Alzheimer’s disease (AD) progression and pathology show pronounced sex differences, but the factors driving these remain poorly understood. To gain insights into early AD-associated molecular changes and their sex dependency for tau pathology in the cortex, we performed single-cell RNA-seq in the THY-Tau22 AD mouse model. By examining cell type-spe...
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Single cell transcriptome analysis of the THY-Tau22 mouse model of Alzheimer’s disease reveals sex-dependent dysregulations
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TN_cdi_doaj_primary_oai_doaj_org_article_84ce9f86bee048dab648269413092647
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_84ce9f86bee048dab648269413092647
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ISSN
2058-7716
E-ISSN
2058-7716
DOI
10.1038/s41420-024-01885-9
