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ArticlesPeer ReviewedFull Text
Single-cell transcriptomics reveals multiple neuronal cell types in human midbrain-specific organoids
Author / Creator:Smits, Lisa M. ; Magni, Stefano ; Kinugawa, Kaoru ; Grzyb, Kamil ; Luginbühl, Joachim ; Sabate-Soler, Sonia ; Bolognin, Silvia ; Shin, Jay W. ; Mori, Eiichiro ; Skupin, Alexander ; Schwamborn, Jens C.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Cell and tissue research, 2020-12, Vol.382 (3), p.463-476
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Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology
Author / Creator:Golebiewska, Anna ; Hau, Ann-Christin ; Oudin, Anaïs ; Stieber, Daniel ; Yabo, Yahaya A. ; Baus, Virginie ; Barthelemy, Vanessa ; Klein, Eliane ; Bougnaud, Sébastien ; Keunen, Olivier ; Wantz, May ; Michelucci, Alessandro ; Neirinckx, Virginie ; Muller, Arnaud ; Kaoma, Tony ; Nazarov, Petr V. ; Azuaje, Francisco ; De Falco, Alfonso ; Flies, Ben ; Richart, Lorraine ; Poovathingal, Suresh ; Arns, Thais ; Grzyb, Kamil ; Mock, Andreas ; Herold-Mende, Christel ; Steino, Anne ; Brown, Dennis ; May, Patrick ; Miletic, Hrvoje ; Malta, Tathiane M. ; Noushmehr, Houtan ; Kwon, Yong-Jun ; Jahn, Winnie ; Klink, Barbara ; Tanner, Georgette ; Stead, Lucy F. ; Mittelbronn, Michel ; Skupin, Alexander ; Hertel, Frank ; Bjerkvig, Rolf ; Niclou, Simone P.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Acta neuropathologica, 2020-12, Vol.140 (6), p.919-949
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ArticlesPeer ReviewedFull Text
Early-to-mid stage idiopathic Parkinson’s disease shows enhanced cytotoxicity and differentiation in CD8 T-cells in females
Author / Creator:Capelle, Christophe M. ; Ciré, Séverine ; Hedin, Fanny ; Hansen, Maxime ; Pavelka, Lukas ; Grzyb, Kamil ; Kyriakis, Dimitrios ; Hunewald, Oliver ; Konstantinou, Maria ; Revets, Dominique ; Tslaf, Vera ; Marques, Tainá M. ; Gomes, Clarissa P. C. ; Baron, Alexandre ; Domingues, Olivia ; Gomez, Mario ; Zeng, Ni ; Betsou, Fay ; May, Patrick ; Skupin, Alexander ; Cosma, Antonio ; Balling, Rudi ; Krüger, Rejko ; Ollert, Markus ; Hefeng, Feng Q.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-11, Vol.14 (1), p.7461-7461, Article 7461
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Single-cell transcriptomics of human iPSC differentiation dynamics reveal a core molecular network of Parkinson’s disease
Author / Creator:Novak, Gabriela ; Kyriakis, Dimitrios ; Grzyb, Kamil ; Bernini, Michela ; Rodius, Sophie ; Dittmar, Gunnar ; Finkbeiner, Steven ; Skupin, Alexander
Publisher:London: Nature Publishing Group UK
Journal title:Communications biology, 2022-01, Vol.5 (1), p.49-49, Article 49
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ArticlesPeer ReviewedFull Text
Elucidating tumour‐associated microglia/macrophage diversity along glioblastoma progression and under ACOD1 deficiency
Author / Creator:Pires‐Afonso, Yolanda ; Muller, Arnaud ; Grzyb, Kamil ; Oudin, Anaïs ; Yabo, Yahaya A. ; Sousa, Carole ; Scafidi, Andrea ; Poli, Aurélie ; Cosma, Antonio ; Halder, Rashi ; Coowar, Djalil ; Golebiewska, Anna ; Skupin, Alexander ; Niclou, Simone P. ; Michelucci, Alessandro
Publisher:Hoboken: John Wiley & Sons, Inc
Journal title:Molecular oncology, 2022-09, Vol.16 (17), p.3167-3191
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Temporal transcriptomic changes in the THY-Tau22 mouse model of tauopathy display cell type- and sex-specific differences
Author / Creator:Ali, Muhammad ; Garcia, Pierre ; Lunkes, Laetitia P. ; Sciortino, Alessia ; Thomas, Melanie H. ; Heurtaux, Tony ; Grzyb, Kamil ; Halder, Rashi ; Skupin, Alexander ; Buée, Luc ; Blum, David ; Buttini, Manuel ; Glaab, Enrico
Publisher:England: BioMed Central
Journal title:Acta neuropathologica communications, 2025-05, Vol.13 (1), p.93-27, Article 93
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Glioblastoma-instructed microglia transition to heterogeneous phenotypic states with phagocytic and dendritic cell-like features in patient tumors and patient-derived orthotopic xenografts
Author / Creator:Yabo, Yahaya A. ; Moreno-Sanchez, Pilar M. ; Pires-Afonso, Yolanda ; Kaoma, Tony ; Nosirov, Bakhtiyor ; Scafidi, Andrea ; Ermini, Luca ; Lipsa, Anuja ; Oudin, Anaïs ; Kyriakis, Dimitrios ; Grzyb, Kamil ; Poovathingal, Suresh K. ; Poli, Aurélie ; Muller, Arnaud ; Toth, Reka ; Klink, Barbara ; Berchem, Guy ; Berthold, Christophe ; Hertel, Frank ; Mittelbronn, Michel ; Heiland, Dieter H. ; Skupin, Alexander ; Nazarov, Petr V. ; Niclou, Simone P. ; Michelucci, Alessandro ; Golebiewska, Anna
Publisher:England: BioMed Central Ltd
Journal title:Genome medicine, 2024-04, Vol.16 (1), p.51-29, Article 51
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ArticlesPeer ReviewedFull Text
Single-nuclei chromatin profiling of ventral midbrain reveals cell identity transcription factors and cell-type-specific gene regulatory variation
Author / Creator:Gui, Yujuan ; Grzyb, Kamil ; Thomas, Mélanie H. ; Ohnmacht, Jochen ; Garcia, Pierre ; Buttini, Manuel ; Skupin, Alexander ; Sauter, Thomas ; Sinkkonen, Lasse
Publisher:England: BioMed Central Ltd
Journal title:Epigenetics & chromatin, 2021-09, Vol.14 (1), p.43-43, Article 43
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ArticlesPeer ReviewedFull Text
Single cell transcriptome analysis of the THY-Tau22 mouse model of Alzheimer’s disease reveals sex-dependent dysregulations
Author / Creator:Ali, Muhammad ; Garcia, Pierre ; Lunkes, Laetitia P. ; Sciortino, Alessia ; Thomas, Melanie ; Heurtaux, Tony ; Grzyb, Kamil ; Halder, Rashi ; Coowar, Djalil ; Skupin, Alex ; Buée, Luc ; Blum, David ; Buttini, Manuel ; Glaab, Enrico
Publisher:London: Nature Publishing Group UK
Journal title:Cell death discovery, 2024-03, Vol.10 (1), p.119-119, Article 119
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ArticlesPeer ReviewedFull Text
Single-Cell Transcriptional Profiling and Gene Regulatory Network Modeling in Tg2576 Mice Reveal Gender-Dependent Molecular Features Preceding Alzheimer-Like Pathologies
Author / Creator:Ali, Muhammad ; Huarte, Oihane Uriarte ; Heurtaux, Tony ; Garcia, Pierre ; Rodriguez, Beatriz Pardo ; Grzyb, Kamil ; Halder, Rashi ; Skupin, Alexander ; Buttini, Manuel ; Glaab, Enrico
Publisher:New York: Springer US
Journal title:Molecular neurobiology, 2024-02, Vol.61 (2), p.541-566
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ArticlesFull Text
Single-cell transcriptomics reveals multiple neuronal cell types in human midbrain-specific organoids
Author / Creator:Smits, Lisa M ; Magni, Stefano ; Grzyb, Kamil ; Paul Ma Antony ; Krueger, Rejko ; Skupin, Alexander ; Bolognin, Silvia ; Schwamborn, Jens
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2019-03
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ArticlesFull Text
Glioblastoma-instructed microglia transition to heterogeneous phenotypic states with phagocytic and dendritic cell-like features in patient tumors and patient-derived orthotopic xenografts
Author / Creator:Yabo, Yahaya A ; Moreno-Sanchez, Pilar M ; Pires-Afonso, Yolanda ; Kaoma, Tony ; Nosirov, Bakhtiyor ; Scafidi, Andrea ; Ermini, Luca ; Lipsa, Anuja ; Oudin, Anais ; Kyriakis, Dimitrios ; Grzyb, Kamil ; Poovathingal, Suresh K ; Poli, Aurelie ; Muller, Arnaud ; Toth, Reka ; Klink, Barbara ; Berchem, Guy ; Berthold, Christophe ; Hertel, Frank ; Mittelbronn, Michel ; Heiland, Dieter H ; Skupin, Alexander ; Nazarov, Petr V ; Niclou, Simone P ; Michelucci, Alessandro ; Golebiewska, Anna
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2023-12
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DatasetsFull Text
CyTOF and Flow Cytometry dataset assocaited with "Early-to-mid stage idiopathic Parkinson's disease shows enhanced cytotoxicity and differentiation in CD8 T-cells in females"
Author / Creator:Capelle, Christophe M. ; Ciré, Séverine ; Hedin, Fanny ; Hansen, Maxime ; Pavelka, Lukas ; Grzyb, Kamil ; Kyriakis, Dimitrios ; Hunewald, Oliver ; Konstantinou, Maria ; Revets, Dominique ; Tslaf, Vera ; Marques, Tainá M. ; Gomes, Clarissa P. C. ; Baron, Alexandre ; Domingues, Olivia ; Gomez, Mario ; Zeng, Ni ; Betsou, Fay ; May, Patrick ; Skupin, Alexander ; Cosma, Antonio ; Balling, Rudi ; Krüger, Rejko ; Ollert, Markus ; Hefeng, Feng Q.
Publisher:Zenodo
Date:2023
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ArticlesFull Text
Single nuclei chromatin profiling of ventral midbrain reveals cell identity transcription factors and cell type-specific gene regulatory variation
Author / Creator:Gui, Yujuan ; Grzyb, Kamil ; Thomas, Mélanie H ; Ohnmacht, Jochen ; Garcia, Pierre ; Buttini, Manuel ; Skupin, Alexander ; Sauter, Thomas ; Sinkkonen, Lasse
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2021-03
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Web ResourcesPeer ReviewedFull Text
Primary and recurrent glioma patient-derived orthotopic xenografts (PDOX) represent relevant patient avatars for precision medicine
Author / Creator:Golebiewska, Anna ; Hau, Ann-Christin ; Oudin, Anaïs ; Stieber, Daniel ; Yabo, Yahaya ; Baus, Virginie ; Barthélémy, Vanessa ; Klein, Eliane ; Bougnaud, Sébastien ; Keunen, Olivier ; Wantz, May ; Michelucci, Alessandro ; Neirinckx, Virginie ; Muller, Arnaud ; Kaoma, Tony ; Nazarov, Petr ; Azuaje, Francisco ; De Falco, Alfonso ; Flies, Ben ; Richart, Lorraine ; Poovathingal, Suresh ; Arns, Thais ; Grzyb, Kamil ; Mock, Andreas ; Herold-Mende, Christel ; Steino, Anne ; Brown, Dennis ; May, Patrick ; Miletic, Hrvoje ; Malta, Tathiane ; Noushmehr, Houtan ; Kwon, Yong-Jun ; Jahn, Winnie ; Klink, Barbara ; Tanner, Georgette ; Stead, Lucy ; Mittelbronn, Michel ; Skupin, Alexander ; Hertel, Frank ; Bjerkvig, Rolf ; Niclou, Simone
Publisher:Springer
Date:2020
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ArticlesFull Text
Primary and recurrent glioma patient-derived orthotopic xenografts (PDOX) represent relevant patient avatars for precision medicine
Author / Creator:Golebiewska, Anna ; Hau, Ann-Christin ; Oudin, Anais ; Stieber, Daniel ; Yabo, Yahaya A ; Baus, Virginie ; Barthelemy, Vanessa ; Klein, Eliane ; Bougnaud, Sebastien ; Keunen, Olivier ; Wantz, May ; Michelucci, Alessandro ; Neirinckx, Virginie ; Muller, Arnaud ; Kaoma, Tony ; Nazarov, Petr V ; Azuaje, Francisco ; De Falco, Alfonso ; Flies, Ben ; Richart, Lorraine ; Poovathingal, Suresh ; Arns, Thais ; Grzyb, Kamil ; Mock, Andreas ; Herold-Mende, Christel ; Steino, Anne ; Brown, Dennis ; May, Patrick ; Miletic, Hrvoje ; Malta, Tathiane M ; Noushmehr, Houtan ; Yong-Jun, Kwon ; Jahn, Winnie ; Klink, Barbara ; Tanner, Georgette ; Stead, Lucy F ; Mittelbronn, Michel ; Skupin, Alexander ; Hertel, Frank ; Bjerkvig, Rolf ; Niclou, Simone P
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2020-04
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Single-cell transcriptomics reveals multiple neuronal cell types in human midbrain-specific organoids

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Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology

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Early-to-mid stage idiopathic Parkinson’s disease shows enhanced cytotoxicity and differentiation in CD8 T-cells in females

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Single-cell transcriptomics of human iPSC differentiation dynamics reveal a core molecular network of Parkinson’s disease

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Elucidating tumour‐associated microglia/macrophage diversity along glioblastoma progression and under ACOD1 deficiency

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Temporal transcriptomic changes in the THY-Tau22 mouse model of tauopathy display cell type- and sex-specific differences

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Glioblastoma-instructed microglia transition to heterogeneous phenotypic states with phagocytic and dendritic cell-like features in patient tumors and patient-derived orthotopic xenografts

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Single-nuclei chromatin profiling of ventral midbrain reveals cell identity transcription factors and cell-type-specific gene regulatory variation

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Single cell transcriptome analysis of the THY-Tau22 mouse model of Alzheimer’s disease reveals sex-dependent dysregulations

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Single-Cell Transcriptional Profiling and Gene Regulatory Network Modeling in Tg2576 Mice Reveal Gender-Dependent Molecular Features Preceding Alzheimer-Like Pathologies

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Single-cell transcriptomics reveals multiple neuronal cell types in human midbrain-specific organoids

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Glioblastoma-instructed microglia transition to heterogeneous phenotypic states with phagocytic and dendritic cell-like features in patient tumors and patient-derived orthotopic xenografts

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CyTOF and Flow Cytometry dataset assocaited with "Early-to-mid stage idiopathic Parkinson's disease shows enhanced cytotoxicity and differentiation in CD8 T-cells in females"

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Single nuclei chromatin profiling of ventral midbrain reveals cell identity transcription factors and cell type-specific gene regulatory variation

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Primary and recurrent glioma patient-derived orthotopic xenografts (PDOX) represent relevant patient avatars for precision medicine

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Primary and recurrent glioma patient-derived orthotopic xenografts (PDOX) represent relevant patient avatars for precision medicine

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