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Leveraging single-cell ATAC-seq and RNA-seq to identify disease-critical fetal and adult brain cell...

Leveraging single-cell ATAC-seq and RNA-seq to identify disease-critical fetal and adult brain cell...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_85297281a64c4afc81f239e94e41ce07

Leveraging single-cell ATAC-seq and RNA-seq to identify disease-critical fetal and adult brain cell types

About this item

Full title

Leveraging single-cell ATAC-seq and RNA-seq to identify disease-critical fetal and adult brain cell types

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2024-01, Vol.15 (1), p.563-11, Article 563

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Prioritizing disease-critical cell types by integrating genome-wide association studies (GWAS) with functional data is a fundamental goal. Single-cell chromatin accessibility (scATAC-seq) and gene expression (scRNA-seq) have characterized cell types at high resolution, and studies integrating GWAS with scRNA-seq have shown promise, but studies inte...

Alternative Titles

Full title

Leveraging single-cell ATAC-seq and RNA-seq to identify disease-critical fetal and adult brain cell types

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_85297281a64c4afc81f239e94e41ce07

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_85297281a64c4afc81f239e94e41ce07

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-024-44742-0

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