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Human metallo-β-lactamase enzymes degrade penicillin

Human metallo-β-lactamase enzymes degrade penicillin

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_85f64b16e26b4baca5d5358296d9896c

Human metallo-β-lactamase enzymes degrade penicillin

About this item

Full title

Human metallo-β-lactamase enzymes degrade penicillin

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2019-08, Vol.9 (1), p.12173-7, Article 12173

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Nonribosomal peptides are assemblages, including antibiotics, of canonical amino acids and other molecules. β-lactam antibiotics act on bacterial cell walls and can be cleaved by β-lactamases. β-lactamase activity in humans has been neglected, even though eighteen enzymes have already been annotated such in human genome. Their hydrolysis activities...

Alternative Titles

Full title

Human metallo-β-lactamase enzymes degrade penicillin

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_85f64b16e26b4baca5d5358296d9896c

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_85f64b16e26b4baca5d5358296d9896c

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-019-48723-y

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