Profilin 1 deficiency drives mitotic defects and reduces genome stability
Profilin 1 deficiency drives mitotic defects and reduces genome stability
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Profilin 1—encoded by
PFN1—
is a small actin-binding protein with a tumour suppressive role in various adenocarcinomas and pagetic osteosarcomas. However, its contribution to tumour development is not fully understood. Using fix and live cell imaging, we report that Profilin 1 inactivation results in multiple mitotic defects, manifested promi...
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Profilin 1 deficiency drives mitotic defects and reduces genome stability
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TN_cdi_doaj_primary_oai_doaj_org_article_8609517adcae44f0a77a5dd393eabeec
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8609517adcae44f0a77a5dd393eabeec
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ISSN
2399-3642
E-ISSN
2399-3642
DOI
10.1038/s42003-022-04392-8
