CKIP-1 limits foam cell formation and inhibits atherosclerosis by promoting degradation of Oct-1 by...
CKIP-1 limits foam cell formation and inhibits atherosclerosis by promoting degradation of Oct-1 by REGγ
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Author / Creator
Fan, Jiao , Liu, Lifeng , Liu, Qingyan , Cui, Yu , Yao, Binwei , Zhang, Minghua , Gao, Yabing , Fu, Yesheng , Dai, Hongmiao , Pan, Jingkun , Qiu, Ya , Liu, Cui Hua , He, Fuchu , Wang, Yu and Zhang, Lingqiang
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Atherosclerosis-related cardiovascular diseases are the leading cause of mortality worldwide. Macrophages uptake modified lipoproteins and transform into foam cells, triggering an inflammatory response and thereby promoting plaque formation. Here we show that casein kinase 2-interacting protein-1 (CKIP-1) is a suppressor of foam cell formation and...
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Full title
CKIP-1 limits foam cell formation and inhibits atherosclerosis by promoting degradation of Oct-1 by REGγ
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TN_cdi_doaj_primary_oai_doaj_org_article_8646b6638a8d471db392995bb77aa1f4
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8646b6638a8d471db392995bb77aa1f4
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-07895-3