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Dextran-Catechin inhibits angiogenesis by disrupting copper homeostasis in endothelial cells

Dextran-Catechin inhibits angiogenesis by disrupting copper homeostasis in endothelial cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_86957e54d73e492ebf3c69aaf156aadd

Dextran-Catechin inhibits angiogenesis by disrupting copper homeostasis in endothelial cells

About this item

Full title

Dextran-Catechin inhibits angiogenesis by disrupting copper homeostasis in endothelial cells

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2017-08, Vol.7 (1), p.7638-10, Article 7638

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Formation of blood vessels, or angiogenesis, is crucial to cancer progression. Thus, inhibiting angiogenesis can limit the growth and spread of tumors. The natural polyphenol catechin has moderate anti-tumor activity and interacts with copper, which is essential for angiogenesis. Catechin is easily metabolized in the body and this limits its clinic...

Alternative Titles

Full title

Dextran-Catechin inhibits angiogenesis by disrupting copper homeostasis in endothelial cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_86957e54d73e492ebf3c69aaf156aadd

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_86957e54d73e492ebf3c69aaf156aadd

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-017-07452-w

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