Tridimensional infiltration of DNA viruses into the host genome shows preferential contact with acti...
Tridimensional infiltration of DNA viruses into the host genome shows preferential contact with active chromatin
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Whether non-integrated viral DNAs distribute randomly or target specific positions within the higher-order architecture of mammalian genomes remains largely unknown. Here we use Hi-C and viral DNA capture (CHi-C) in primary human hepatocytes infected by either hepatitis B virus (HBV) or adenovirus type 5 (Ad5) virus to show that they adopt differen...
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Full title
Tridimensional infiltration of DNA viruses into the host genome shows preferential contact with active chromatin
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TN_cdi_doaj_primary_oai_doaj_org_article_878cd31675d7462e94de500ad5635813
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_878cd31675d7462e94de500ad5635813
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-06739-4
