Senescent response in inner annulus fibrosus cells in response to TNFα, H2O2, and TNFα-induced nucle...
Senescent response in inner annulus fibrosus cells in response to TNFα, H2O2, and TNFα-induced nucleus pulposus senescent secretome
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Senescence, particularly in the nucleus pulposus (NP) cells, has been implicated in the pathogenesis of disc degeneration, however, the mechanism(s) of annulus fibrosus (AF) cell senescence is still not well understood. Both TNFα and H2O2, have been implicated as contributors to the senescence pathways, and their levels are increased in degenerated...
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Full title
Senescent response in inner annulus fibrosus cells in response to TNFα, H2O2, and TNFα-induced nucleus pulposus senescent secretome
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TN_cdi_doaj_primary_oai_doaj_org_article_8879072453d04cbaa260894da3de6ec7
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8879072453d04cbaa260894da3de6ec7
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0280101
