Effects of ALT-801, a GLP-1 and glucagon receptor dual agonist, in a translational mouse model of no...
Effects of ALT-801, a GLP-1 and glucagon receptor dual agonist, in a translational mouse model of non-alcoholic steatohepatitis
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Body weight loss of ≥ 10% improves the metabolic derangements and liver disease in the majority of non-alcoholic steatohepatitis (NASH) patients, suggesting metabolic modulators may be effective in controlling disease. The pharmacodynamics of ALT-801, a GLP-1/glucagon receptor dual agonist optimized for NASH and weight loss, were compared to semagl...
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Effects of ALT-801, a GLP-1 and glucagon receptor dual agonist, in a translational mouse model of non-alcoholic steatohepatitis
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TN_cdi_doaj_primary_oai_doaj_org_article_897d8fdd47e14640b0e436399f7ccb41
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_897d8fdd47e14640b0e436399f7ccb41
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-022-10577-2
