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Rho-GTPase pathways may differentiate treatment response to TNF-alpha and IL-17A inhibitors in psori...

Rho-GTPase pathways may differentiate treatment response to TNF-alpha and IL-17A inhibitors in psori...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_89afa7b431d842f397da1b39a9b64a04

Rho-GTPase pathways may differentiate treatment response to TNF-alpha and IL-17A inhibitors in psoriatic arthritis

About this item

Full title

Rho-GTPase pathways may differentiate treatment response to TNF-alpha and IL-17A inhibitors in psoriatic arthritis

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2020-12, Vol.10 (1), p.21703-21703, Article 21703

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Biological therapies have dramatically improved the therapeutic landscape of psoriatic arthritis (PsA); however, 40–50% of patients are primary non-responders with response rates declining significantly with each successive biological therapy. Therefore, there is a pressing need to develop a coherent strategy for effective initial and subsequent se...

Alternative Titles

Full title

Rho-GTPase pathways may differentiate treatment response to TNF-alpha and IL-17A inhibitors in psoriatic arthritis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_89afa7b431d842f397da1b39a9b64a04

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_89afa7b431d842f397da1b39a9b64a04

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-020-78866-2

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