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Combination of immune checkpoint blockade with DNA cancer vaccine induces potent antitumor immunity...

Combination of immune checkpoint blockade with DNA cancer vaccine induces potent antitumor immunity...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8a185f7e782e4e90bd9cd7722f8cbb6c

Combination of immune checkpoint blockade with DNA cancer vaccine induces potent antitumor immunity against P815 mastocytoma

About this item

Full title

Combination of immune checkpoint blockade with DNA cancer vaccine induces potent antitumor immunity against P815 mastocytoma

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2018-10, Vol.8 (1), p.15732-11, Article 15732

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

DNA vaccination against cancer has become a promising strategy for inducing a specific and long-lasting antitumor immunity. However, DNA vaccines fail to generate potent immune responses when used as a single therapy. To enhance their activity into the tumor, a DNA vaccine against murine P815 mastocytoma was combined with antibodies directed agains...

Alternative Titles

Full title

Combination of immune checkpoint blockade with DNA cancer vaccine induces potent antitumor immunity against P815 mastocytoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_8a185f7e782e4e90bd9cd7722f8cbb6c

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8a185f7e782e4e90bd9cd7722f8cbb6c

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-018-33933-7

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