N 6 -methyladenosine regulates glycolysis of cancer cells through PDK4
N 6 -methyladenosine regulates glycolysis of cancer cells through PDK4
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Author / Creator
Li, Zihan , Peng, Yanxi , Li, Jiexin , Chen, Zhuojia , Chen, Feng , Tu, Jian , Lin, Shuibin and Wang, Hongsheng
Publisher
England: Nature Portfolio
Journal title
Language
English
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Publisher
England: Nature Portfolio
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Contents
Studies on biological functions of N
-methyladenosine (m
A) modification in mRNA have sprung up in recent years. We find m
A can positively regulate the glycolysis of cancer cells. Specifically, m
A-sequencing and functional studies confirm that pyruvate dehydrogenase kinase 4 (PDK4) is involved in m
A regulated glycolysis and ATP ge...
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Full title
N 6 -methyladenosine regulates glycolysis of cancer cells through PDK4
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TN_cdi_doaj_primary_oai_doaj_org_article_8ad24c716e8548f1a29032ce576d9050
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8ad24c716e8548f1a29032ce576d9050
Other Identifiers
E-ISSN
2041-1723
DOI
10.1038/s41467-020-16306-5
