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Peripheral administration of nanomicelle-encapsulated anti-Aβ oligomer fragment antibody reduces var...

Peripheral administration of nanomicelle-encapsulated anti-Aβ oligomer fragment antibody reduces var...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8b45c3e51a3b4087b398375c02604d43

Peripheral administration of nanomicelle-encapsulated anti-Aβ oligomer fragment antibody reduces various toxic Aβ species in the brain

About this item

Full title

Peripheral administration of nanomicelle-encapsulated anti-Aβ oligomer fragment antibody reduces various toxic Aβ species in the brain

Publisher

England: BioMed Central

Journal title

Journal of nanobiotechnology, 2023-01, Vol.21 (1), p.36-36, Article 36

Language

English

Formats

Publication information

Publisher

England: BioMed Central

More information

Scope and Contents

Contents

Although a large amount of evidence has revealed that amyloid β (Aβ), especially Aβ oligomers, protofibrils, and pyroglutamated Aβs, participate primarily in the pathophysiological processes of Alzheimer's disease, most clinical trials of anti-Aβ antibody therapy have never acquired successful efficacy in human clinical trials, partly because perip...

Alternative Titles

Full title

Peripheral administration of nanomicelle-encapsulated anti-Aβ oligomer fragment antibody reduces various toxic Aβ species in the brain

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_8b45c3e51a3b4087b398375c02604d43

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8b45c3e51a3b4087b398375c02604d43

Other Identifiers

ISSN

1477-3155

E-ISSN

1477-3155

DOI

10.1186/s12951-023-01772-y

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