Transcriptomic profiling of early synucleinopathy in rats induced with preformed fibrils
Transcriptomic profiling of early synucleinopathy in rats induced with preformed fibrils
About this item
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Author / Creator
Patterson, Joseph R. , Kochmanski, Joseph , Stoll, Anna C. , Kubik, Michael , Kemp, Christopher J. , Duffy, Megan F. , Thompson, Kajene , Howe, Jacob W. , Cole-Strauss, Allyson , Kuhn, Nathan C. , Miller, Kathryn M. , Nelson, Seth , Onyekpe, Christopher U. , Beck, John S. , Counts, Scott E. , Bernstein, Alison I. , Steece-Collier, Kathy , Luk, Kelvin C. and Sortwell, Caryl E.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Examination of early phases of synucleinopathy when inclusions are present, but long before neurodegeneration occurs, is critical to both understanding disease progression and the development of disease modifying therapies. The rat alpha-synuclein (α-syn) preformed fibril (PFF) model induces synchronized synucleinopathy that recapitulates the patho...
Alternative Titles
Full title
Transcriptomic profiling of early synucleinopathy in rats induced with preformed fibrils
Authors, Artists and Contributors
Author / Creator
Kochmanski, Joseph
Stoll, Anna C.
Kubik, Michael
Kemp, Christopher J.
Duffy, Megan F.
Thompson, Kajene
Howe, Jacob W.
Cole-Strauss, Allyson
Kuhn, Nathan C.
Miller, Kathryn M.
Nelson, Seth
Onyekpe, Christopher U.
Beck, John S.
Counts, Scott E.
Bernstein, Alison I.
Steece-Collier, Kathy
Luk, Kelvin C.
Sortwell, Caryl E.
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_8bde4016617e4debb09532f2fc4a2cc0
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8bde4016617e4debb09532f2fc4a2cc0
Other Identifiers
ISSN
2373-8057
E-ISSN
2373-8057
DOI
10.1038/s41531-023-00620-y
