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Expression of E-cadherin by CD8+ T cells promotes their invasion into biliary epithelial cells

Expression of E-cadherin by CD8+ T cells promotes their invasion into biliary epithelial cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8c5d5d80fa404d79a9d64d2f03722925

Expression of E-cadherin by CD8+ T cells promotes their invasion into biliary epithelial cells

About this item

Full title

Expression of E-cadherin by CD8+ T cells promotes their invasion into biliary epithelial cells

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2024-01, Vol.15 (1), p.853-22, Article 853

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The presence of CD8
+
T cells in the cytoplasm of biliary epithelial cells (BEC) has been correlated with biliary damage associated with primary biliary cholangitis (PBC). Here, we characterise the mechanism of CD8
+
T cell invasion into BEC. CD8
+
T cells observed within BEC were large, eccentric, and expressed E-cadherin, CD103...

Alternative Titles

Full title

Expression of E-cadherin by CD8+ T cells promotes their invasion into biliary epithelial cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_8c5d5d80fa404d79a9d64d2f03722925

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8c5d5d80fa404d79a9d64d2f03722925

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-024-44910-2

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