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Transcriptional dynamics of murine motor neuron maturation in vivo and in vitro

Transcriptional dynamics of murine motor neuron maturation in vivo and in vitro

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8c6a3121fd1145a590671bdfc9c21b17

Transcriptional dynamics of murine motor neuron maturation in vivo and in vitro

About this item

Full title

Transcriptional dynamics of murine motor neuron maturation in vivo and in vitro

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2022-09, Vol.13 (1), p.5427-5427, Article 5427

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Neurons born in the embryo can undergo a protracted period of maturation lasting well into postnatal life. How gene expression changes are regulated during maturation and whether they can be recapitulated in cultured neurons remains poorly understood. Here, we show that mouse motor neurons exhibit pervasive changes in gene expression and accessibil...

Alternative Titles

Full title

Transcriptional dynamics of murine motor neuron maturation in vivo and in vitro

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_8c6a3121fd1145a590671bdfc9c21b17

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8c6a3121fd1145a590671bdfc9c21b17

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-022-33022-4

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