Wnt/Beta-catenin/Esrrb signalling controls the tissue-scale reorganization and maintenance of the pl...
Wnt/Beta-catenin/Esrrb signalling controls the tissue-scale reorganization and maintenance of the pluripotent lineage during murine embryonic diapause
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The epiblast, which provides the foundation of the future body, is actively reshaped during early embryogenesis, but the reshaping mechanisms are poorly understood. Here, using a 3D in vitro model of early epiblast development, we identify the canonical Wnt/β-catenin pathway and its central downstream factor Esrrb as the key signalling cascade regu...
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Wnt/Beta-catenin/Esrrb signalling controls the tissue-scale reorganization and maintenance of the pluripotent lineage during murine embryonic diapause
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TN_cdi_doaj_primary_oai_doaj_org_article_8ca51a4f837f4e888adc4dfe1fda8fa3
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8ca51a4f837f4e888adc4dfe1fda8fa3
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-19353-0
