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ArticlesPeer ReviewedFull Text
Investigating human disease using stem cell models
Author / Creator:Sterneckert, Jared L. ; Reinhardt, Peter ; Schöler, Hans R.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Genetics, 2014-09, Vol.15 (9), p.625-639
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Rapid and efficient generation of oligodendrocytes from human induced pluripotent stem cells using transcription factors
Author / Creator:Ehrlich, Marc ; Mozafari, Sabah ; Glatza, Michael ; Starost, Laura ; Velychko, Sergiy ; Hallmann, Anna-Lena ; Cui, Qiao-Ling ; Schambach, Axel ; Kim, Kee-Pyo ; Bachelin, Corinne ; Marteyn, Antoine ; Hargus, Gunnar ; Johnson, Radia Marie ; Antel, Jack ; Sterneckert, Jared ; Zaehres, Holm ; Schöler, Hans R. ; Evercooren, Anne Baron-Van ; Kuhlmann, Tanja
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2017-03, Vol.114 (11), p.E2243-E2252
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ArticlesPeer ReviewedFull Text
Direct reprogramming of human neural stem cells by OCT4
Author / Creator:Kim, Jeong Beom ; Greber, Boris ; Araúzo-Bravo, Marcos J. ; Meyer, Johann ; Park, Kook In ; Zaehres, Holm ; Schöler, Hans R.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2009-10, Vol.461 (7264), p.649-653
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ArticlesPeer ReviewedFull Text
Regulatory networks in embryo-derived pluripotent stem cells
Author / Creator:Boiani, Michele ; Schöler, Hans R
Publisher:England: Nature Publishing Group
Journal title:Nature reviews. Molecular cell biology, 2005-11, Vol.6 (11), p.872-881
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ArticlesPeer ReviewedFull Text
Derivation and expansion using only small molecules of human neural progenitors for neurodegenerative disease modeling
Author / Creator:Reinhardt, Peter ; Glatza, Michael ; Hemmer, Kathrin ; Tsytsyura, Yaroslav ; Thiel, Cora S ; Höing, Susanne ; Moritz, Sören ; Parga, Juan A ; Wagner, Lydia ; Bruder, Jan M ; Wu, Guangming ; Schmid, Benjamin ; Röpke, Albrecht ; Klingauf, Jürgen ; Schwamborn, Jens C ; Gasser, Thomas ; Schöler, Hans R ; Sterneckert, Jared
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-03, Vol.8 (3), p.e59252-e59252
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ArticlesPeer ReviewedFull Text
DNA methylation regulates discrimination of enhancers from promoters through a H3K4me1-H3K4me3 seesaw mechanism
Author / Creator:Sharifi-Zarchi, Ali ; Gerovska, Daniela ; Adachi, Kenjiro ; Totonchi, Mehdi ; Pezeshk, Hamid ; Taft, Ryan J ; Schöler, Hans R ; Chitsaz, Hamidreza ; Sadeghi, Mehdi ; Baharvand, Hossein ; Araúzo-Bravo, Marcos J
Publisher:England: BioMed Central Ltd
Journal title:BMC genomics, 2017-12, Vol.18 (1), p.964-964, Article 964
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ArticlesPeer ReviewedFull Text
Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors
Author / Creator:Kim, Jeong Beom ; Zaehres, Holm ; Wu, Guangming ; Gentile, Luca ; Ko, Kinarm ; Sebastiano, Vittorio ; Araúzo-Bravo, Marcos J. ; Ruau, David ; Han, Dong Wook ; Zenke, Martin ; Schöler, Hans R.
Publisher:London: Nature Publishing Group UK
Journal title:Nature, 2008-07, Vol.454 (7204), p.646-650
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ArticlesPeer ReviewedFull Text
Genome-wide tracking of dCas9-methyltransferase footprints
Author / Creator:Galonska, Christina ; Charlton, Jocelyn ; Mattei, Alexandra L. ; Donaghey, Julie ; Clement, Kendell ; Gu, Hongcang ; Mohammad, Arman W. ; Stamenova, Elena K. ; Cacchiarelli, Davide ; Klages, Sven ; Timmermann, Bernd ; Cantz, Tobias ; Schöler, Hans R. ; Gnirke, Andreas ; Ziller, Michael J. ; Meissner, Alexander
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-02, Vol.9 (1), p.597-9, Article 597
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ArticlesPeer ReviewedFull Text
Wnt/Beta-catenin/Esrrb signalling controls the tissue-scale reorganization and maintenance of the pluripotent lineage during murine embryonic diapause
Author / Creator:Fan, Rui ; Kim, Yung Su ; Wu, Jie ; Chen, Rui ; Zeuschner, Dagmar ; Mildner, Karina ; Adachi, Kenjiro ; Wu, Guangming ; Galatidou, Styliani ; Li, Jianhua ; Schöler, Hans R. ; Leidel, Sebastian A. ; Bedzhov, Ivan
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-10, Vol.11 (1), p.5499-5499, Article 5499
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ArticlesPeer ReviewedFull Text
Transcriptional regulation of endothelial cell behavior during sprouting angiogenesis
Author / Creator:Jeong, Hyun-Woo ; Hernández-Rodríguez, Benjamín ; Kim, JungMo ; Kim, Kee-Pyo ; Enriquez-Gasca, Rocio ; Yoon, Juyong ; Adams, Susanne ; Schöler, Hans R. ; Vaquerizas, Juan M. ; Adams, Ralf H.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-09, Vol.8 (1), p.726-14, Article 726
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ArticlesPeer ReviewedFull Text
Pluripotency reprogramming by competent and incompetent POU factors uncovers temporal dependency for Oct4 and Sox2
Author / Creator:Malik, Vikas ; Glaser, Laura V. ; Zimmer, Dennis ; Velychko, Sergiy ; Weng, Mingxi ; Holzner, Markus ; Arend, Marius ; Chen, Yanpu ; Srivastava, Yogesh ; Veerapandian, Veeramohan ; Shah, Zahir ; Esteban, Miguel A. ; Wang, Huating ; Chen, Jiekai ; Schöler, Hans R. ; Hutchins, Andrew P. ; Meijsing, Sebastiaan H. ; Pott, Sebastian ; Jauch, Ralf
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-08, Vol.10 (1), p.3477-16, Article 3477
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ArticlesPeer ReviewedFull Text
Establishment of totipotency does not depend on Oct4A
Author / Creator:Wu, Guangming ; Han, Dong ; Gong, Yu ; Sebastiano, Vittorio ; Gentile, Luca ; Singhal, Nishant ; Adachi, Kenjiro ; Fischedick, Gerrit ; Ortmeier, Claudia ; Sinn, Martina ; Radstaak, Martina ; Tomilin, Alexey ; Schöler, Hans R.
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2013-09, Vol.15 (9), p.1089-1097
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ArticlesPeer ReviewedFull Text
Directed Evolution of an Enhanced POU Reprogramming Factor for Cell Fate Engineering
Author / Creator:Tan, Daisylyn Senna ; Chen, Yanpu ; Gao, Ya ; Bednarz, Anastasia ; Wei, Yuanjie ; Malik, Vikas ; Ho, Derek Hoi-Hang ; Weng, Mingxi ; Ho, Sik Yin ; Srivastava, Yogesh ; Velychko, Sergiy ; Yang, Xiaoxiao ; Fan, Ligang ; Kim, Johnny ; Graumann, Johannes ; Stormo, Gary D. ; Braun, Thomas ; Yan, Jian ; Schöler, Hans R. ; Jauch, Ralf
Publisher:United States: Oxford University Press
Journal title:Molecular biology and evolution, 2021-07, Vol.38 (7), p.2854-2868
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ArticlesPeer ReviewedFull Text
Biological importance of OCT transcription factors in reprogramming and development
Author / Creator:Kim, Kee-Pyo ; Han, Dong Wook ; Kim, Johnny ; Schöler, Hans R.
Publisher:London: Nature Publishing Group UK
Journal title:Experimental and Molecular Medicine, 2021, 53(0), , pp.1-11
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ArticlesPeer ReviewedFull Text
Nfat/calcineurin signaling promotes oligodendrocyte differentiation and myelination by transcription factor network tuning
Author / Creator:Weider, Matthias ; Starost, Laura Julia ; Groll, Katharina ; Küspert, Melanie ; Sock, Elisabeth ; Wedel, Miriam ; Fröb, Franziska ; Schmitt, Christian ; Baroti, Tina ; Hartwig, Anna C. ; Hillgärtner, Simone ; Piefke, Sandra ; Fadler, Tanja ; Ehrlich, Marc ; Ehlert, Corinna ; Stehling, Martin ; Albrecht, Stefanie ; Jabali, Ammar ; Schöler, Hans R. ; Winkler, Jürgen ; Kuhlmann, Tanja ; Wegner, Michael
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-03, Vol.9 (1), p.899-16, Article 899
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ArticlesPeer ReviewedFull Text
Derivation of Oocytes from Mouse Embryonic Stem Cells
Author / Creator:Hübner, Karin ; Fuhrmann, Guy ; Christenson, Lane K. ; Kehler, James ; Reinbold, Rolland ; de la Fuente, Rabindranath ; Wood, Jennifer ; Strauss, Jerome F. ; Boiani, Michele ; Schöler, Hans R.
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2003-05, Vol.300 (5623), p.1251-1256
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ArticlesPeer ReviewedFull Text
Astrocyte pathology in a human neural stem cell model of frontotemporal dementia caused by mutant TAU protein
Author / Creator:Hallmann, Anna-Lena ; Araúzo-Bravo, Marcos J. ; Mavrommatis, Lampros ; Ehrlich, Marc ; Röpke, Albrecht ; Brockhaus, Johannes ; Missler, Markus ; Sterneckert, Jared ; Schöler, Hans R. ; Kuhlmann, Tanja ; Zaehres, Holm ; Hargus, Gunnar
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-03, Vol.7 (1), p.42991-42991, Article 42991
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ArticlesPeer ReviewedFull Text
Lentiviral Vector Design and Imaging Approaches to Visualize the Early Stages of Cellular Reprogramming
Author / Creator:Warlich, Eva ; Kuehle, Johannes ; Cantz, Tobias ; Brugman, Martijn H ; Maetzig, Tobias ; Galla, Melanie ; Filipczyk, Adam A ; Halle, Stephan ; Klump, Hannes ; Schöler, Hans R ; Baum, Christopher ; Schroeder, Timm ; Schambach, Axel
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy, 2011-04, Vol.19 (4), p.782-789
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ArticlesPeer ReviewedFull Text
Small molecule-assisted, line-independent maintenance of human pluripotent stem cells in defined conditions
Author / Creator:Frank, Stefan ; Zhang, Miao ; Schöler, Hans R ; Greber, Boris
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-07, Vol.7 (7), p.e41958-e41958
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ArticlesPeer ReviewedFull Text
A unique Oct4 interface is crucial for reprogramming to pluripotency
Author / Creator:Esch, Daniel ; Vahokoski, Juha ; Groves, Matthew R. ; Pogenberg, Vivian ; Cojocaru, Vlad ; vom Bruch, Hermann ; Han, Dong ; Drexler, Hannes C. A. ; Araúzo-Bravo, Marcos J. ; Ng, Calista K. L. ; Jauch, Ralf ; Wilmanns, Matthias ; Schöler, Hans R.
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2013-03, Vol.15 (3), p.295-301
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Investigating human disease using stem cell models

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Rapid and efficient generation of oligodendrocytes from human induced pluripotent stem cells using transcription factors

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Direct reprogramming of human neural stem cells by OCT4

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Regulatory networks in embryo-derived pluripotent stem cells

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Derivation and expansion using only small molecules of human neural progenitors for neurodegenerative disease modeling

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DNA methylation regulates discrimination of enhancers from promoters through a H3K4me1-H3K4me3 seesaw mechanism

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Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors

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Genome-wide tracking of dCas9-methyltransferase footprints

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Wnt/Beta-catenin/Esrrb signalling controls the tissue-scale reorganization and maintenance of the pluripotent lineage during murine embryonic diapause

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Transcriptional regulation of endothelial cell behavior during sprouting angiogenesis

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Pluripotency reprogramming by competent and incompetent POU factors uncovers temporal dependency for Oct4 and Sox2

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Establishment of totipotency does not depend on Oct4A

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Directed Evolution of an Enhanced POU Reprogramming Factor for Cell Fate Engineering

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Biological importance of OCT transcription factors in reprogramming and development

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Nfat/calcineurin signaling promotes oligodendrocyte differentiation and myelination by transcription factor network tuning

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Derivation of Oocytes from Mouse Embryonic Stem Cells

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Astrocyte pathology in a human neural stem cell model of frontotemporal dementia caused by mutant TAU protein

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Lentiviral Vector Design and Imaging Approaches to Visualize the Early Stages of Cellular Reprogramming

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Small molecule-assisted, line-independent maintenance of human pluripotent stem cells in defined conditions

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A unique Oct4 interface is crucial for reprogramming to pluripotency

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