Empagliflozin reduces podocyte lipotoxicity in experimental Alport syndrome
Empagliflozin reduces podocyte lipotoxicity in experimental Alport syndrome
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England: eLife Sciences Publications Ltd
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English
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England: eLife Sciences Publications Ltd
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Sodium-glucose cotransporter-2 inhibitors (SGLT2i) are anti-hyperglycemic agents that prevent glucose reabsorption in proximal tubular cells. SGLT2i improves renal outcomes in both diabetic and non-diabetic patients, indicating it may have beneficial effects beyond glycemic control. Here, we demonstrate that SGLT2i affects energy metabolism and pod...
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Empagliflozin reduces podocyte lipotoxicity in experimental Alport syndrome
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TN_cdi_doaj_primary_oai_doaj_org_article_8d37cf2ae9d140ee9fdc28b97b8e5e79
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8d37cf2ae9d140ee9fdc28b97b8e5e79
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.83353