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Empagliflozin reduces podocyte lipotoxicity in experimental Alport syndrome

Empagliflozin reduces podocyte lipotoxicity in experimental Alport syndrome

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8d37cf2ae9d140ee9fdc28b97b8e5e79

Empagliflozin reduces podocyte lipotoxicity in experimental Alport syndrome

About this item

Full title

Empagliflozin reduces podocyte lipotoxicity in experimental Alport syndrome

Publisher

England: eLife Sciences Publications Ltd

Journal title

eLife, 2023-05, Vol.12

Language

English

Formats

Publication information

Publisher

England: eLife Sciences Publications Ltd

More information

Scope and Contents

Contents

Sodium-glucose cotransporter-2 inhibitors (SGLT2i) are anti-hyperglycemic agents that prevent glucose reabsorption in proximal tubular cells. SGLT2i improves renal outcomes in both diabetic and non-diabetic patients, indicating it may have beneficial effects beyond glycemic control. Here, we demonstrate that SGLT2i affects energy metabolism and pod...

Alternative Titles

Full title

Empagliflozin reduces podocyte lipotoxicity in experimental Alport syndrome

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_8d37cf2ae9d140ee9fdc28b97b8e5e79

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8d37cf2ae9d140ee9fdc28b97b8e5e79

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.83353

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