Ablation of Bscl2 /seipin in hepatocytes does not cause metabolic dysfunction in congenital generali...
Ablation of Bscl2 /seipin in hepatocytes does not cause metabolic dysfunction in congenital generalised lipodystrophy
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Publisher
England: The Company of Biologists Ltd
Journal title
Language
English
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Publisher
England: The Company of Biologists Ltd
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Scope and Contents
Contents
Mutations affecting the
gene cause the most severe form of congenital generalised lipodystrophy (CGL). Affected individuals develop severe metabolic complications including diabetes and hepatic steatosis.
-deficient mice almost entirely reproduce the CGL phenotype. Adipose tissue-specific loss of
is also sufficient to cause early-onset gen...
Alternative Titles
Full title
Ablation of Bscl2 /seipin in hepatocytes does not cause metabolic dysfunction in congenital generalised lipodystrophy
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TN_cdi_doaj_primary_oai_doaj_org_article_8d64762d0fe14cc6ae447f99eaa5483c
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8d64762d0fe14cc6ae447f99eaa5483c
Other Identifiers
ISSN
1754-8403
E-ISSN
1754-8411
DOI
10.1242/dmm.042655
