Simultaneous disruption of two DNA polymerases, Polη and Polζ, in Avian DT40 cells unmasks the role...
Simultaneous disruption of two DNA polymerases, Polη and Polζ, in Avian DT40 cells unmasks the role of Polη in cellular response to various DNA lesions
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Replicative DNA polymerases are frequently stalled by DNA lesions. The resulting replication blockage is released by homologous recombination (HR) and translesion DNA synthesis (TLS). TLS employs specialized TLS polymerases to bypass DNA lesions. We provide striking in vivo evidence of the cooperation between DNA polymerase η, which is mutated in t...
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Simultaneous disruption of two DNA polymerases, Polη and Polζ, in Avian DT40 cells unmasks the role of Polη in cellular response to various DNA lesions
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TN_cdi_doaj_primary_oai_doaj_org_article_8da1f6191d1b461e8ef6c6a2e071181b
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8da1f6191d1b461e8ef6c6a2e071181b
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1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1001151
