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Estrogen Regulates Bone Turnover by Targeting RANKL Expression in Bone Lining Cells

Estrogen Regulates Bone Turnover by Targeting RANKL Expression in Bone Lining Cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8deacb25c8e6455ab90cd1d806872bfd

Estrogen Regulates Bone Turnover by Targeting RANKL Expression in Bone Lining Cells

About this item

Full title

Estrogen Regulates Bone Turnover by Targeting RANKL Expression in Bone Lining Cells

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2017-07, Vol.7 (1), p.6460-14, Article 6460

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Estrogen is critical for skeletal homeostasis and regulates bone remodeling, in part, by modulating the expression of receptor activator of NF-κB ligand (RANKL), an essential cytokine for bone resorption by osteoclasts. RANKL can be produced by a variety of hematopoietic (e.g. T and B-cell) and mesenchymal (osteoblast lineage, chondrocyte) cell typ...

Alternative Titles

Full title

Estrogen Regulates Bone Turnover by Targeting RANKL Expression in Bone Lining Cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_8deacb25c8e6455ab90cd1d806872bfd

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8deacb25c8e6455ab90cd1d806872bfd

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-017-06614-0

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