Metabolic engineering of Streptomyces roseosporus for increased production of clinically important a...
Metabolic engineering of Streptomyces roseosporus for increased production of clinically important antibiotic daptomycin
About this item
Full title
Author / Creator
Li, Xingwang , Sang, Ziwei , Zhao, Xuejin and Wen, Ying
Publisher
United States: John Wiley & Sons, Inc
Journal title
Language
English
Formats
Publication information
Publisher
United States: John Wiley & Sons, Inc
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Scope and Contents
Contents
Daptomycin (DAP), a novel cyclic lipopeptide antibiotic produced by Streptomyces roseosporus, is clinically important for treatment of infections caused by multidrug‐resistant Gram‐positive pathogens, but the low yield hampers its large‐scale industrial production. Here, we describe a combination metabolic engineering strategy for constructing a DA...
Alternative Titles
Full title
Metabolic engineering of Streptomyces roseosporus for increased production of clinically important antibiotic daptomycin
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Author / Creator
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_8f4ff19e8eb641f589da7859a0fbf6fe
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8f4ff19e8eb641f589da7859a0fbf6fe
Other Identifiers
ISSN
1751-7915
E-ISSN
1751-7915
DOI
10.1111/1751-7915.70038
