Caloric restriction leads to druggable LSD1-dependent cancer stem cells expansion
Caloric restriction leads to druggable LSD1-dependent cancer stem cells expansion
About this item
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Author / Creator
Pallavi, Rani , Gatti, Elena , Durfort, Tiphanie , Stendardo, Massimo , Ravasio, Roberto , Leonardi, Tommaso , Falvo, Paolo , Duso, Bruno Achutti , Punzi, Simona , Xieraili, Aobuli , Polazzi, Andrea , Verrelli, Doriana , Trastulli, Deborah , Ronzoni, Simona , Frascolla, Simone , Perticari, Giulia , Elgendy, Mohamed , Varasi, Mario , Colombo, Emanuela , Giorgio, Marco , Lanfrancone, Luisa , Minucci, Saverio , Mazzarella, Luca and Pelicci, Pier Giuseppe
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Caloric Restriction (CR) has established anti-cancer effects, but its clinical relevance and molecular mechanism remain largely undefined. Here, we investigate CR’s impact on several mouse models of Acute Myeloid Leukemias, including Acute Promyelocytic Leukemia, a subtype strongly affected by obesity. After an initial marked anti-tumor effect, let...
Alternative Titles
Full title
Caloric restriction leads to druggable LSD1-dependent cancer stem cells expansion
Authors, Artists and Contributors
Author / Creator
Gatti, Elena
Durfort, Tiphanie
Stendardo, Massimo
Ravasio, Roberto
Leonardi, Tommaso
Falvo, Paolo
Duso, Bruno Achutti
Punzi, Simona
Xieraili, Aobuli
Polazzi, Andrea
Verrelli, Doriana
Trastulli, Deborah
Ronzoni, Simona
Frascolla, Simone
Perticari, Giulia
Elgendy, Mohamed
Varasi, Mario
Colombo, Emanuela
Giorgio, Marco
Lanfrancone, Luisa
Minucci, Saverio
Mazzarella, Luca
Pelicci, Pier Giuseppe
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_8f7683b064194aa894f4ffe6b6a13e8b
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8f7683b064194aa894f4ffe6b6a13e8b
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-44348-y
