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ArticlesPeer ReviewedFull Text
The metabolism of cells regulates their sensitivity to NK cells depending on p53 status
Author / Creator:Belkahla, Sana ; Brualla, Joaquin Marco ; Fayd’herbe de Maudave, Alexis ; Falvo, Paolo ; Allende-Vega, Nerea ; Constantinides, Michael ; Khan, Abrar Ul Haq ; Coenon, Lois ; Alexia, Catherine ; Mitola, Giulia ; Massa, Paul ; Orecchioni, Stefania ; Bertolini, Francesco ; Mnif, Wissem ; Hernandez, Javier ; Anel, Alberto ; Villalba, Martin
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2022-02, Vol.12 (1), p.3234-3234, Article 3234
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Metformin sensitizes leukemic cells to cytotoxic lymphocytes by increasing expression of intercellular adhesion molecule-1 (ICAM-1)
Author / Creator:Allende-Vega, Nerea ; Marco Brualla, Joaquin ; Falvo, Paolo ; Alexia, Catherine ; Constantinides, Michael ; de Maudave, Alexis Fayd’herbe ; Coenon, Lois ; Gitenay, Delphine ; Mitola, Giulia ; Massa, Paul ; Orecchioni, Stefania ; Bertolini, Francesco ; Marzo, Isabel ; Anel, Alberto ; Villalba, Martin
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2022-01, Vol.12 (1), p.1341-12, Article 1341
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BET inhibitors drive Natural Killer activation in non-small cell lung cancer via BRD4 and SMAD3
Author / Creator:Reggiani, Francesca ; Talarico, Giovanna ; Gobbi, Giulia ; Sauta, Elisabetta ; Torricelli, Federica ; Manicardi, Veronica ; Zanetti, Eleonora ; Orecchioni, Stefania ; Falvo, Paolo ; Piana, Simonetta ; Lococo, Filippo ; Paci, Massimiliano ; Bertolini, Francesco ; Ciarrocchi, Alessia ; Sancisi, Valentina
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-03, Vol.15 (1), p.2567-2567, Article 2567
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Dual targeting of the DNA damage response pathway and BCL-2 in diffuse large B-cell lymphoma
Author / Creator:Rossi, Alessandra ; Orecchioni, Stefania ; Falvo, Paolo ; Tabanelli, Valentina ; Baiardi, Elena ; Agostinelli, Claudio ; Melle, Federica ; Motta, Giovanna ; Calleri, Angelica ; Fiori, Stefano ; Corsini, Chiara ; Casadei, Beatrice ; Mazzara, Saveria ; Vitolo, Umberto ; Bertolini, Francesco ; Zinzani, Pier Luigi ; Alcalay, Myriam ; Pelicci, Pier Giuseppe ; Pileri, Stefano ; Tarella, Corrado ; Derenzini, Enrico
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2022-01, Vol.36 (1), p.197-209
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New Insight to Overcome Tumor Resistance: An Overview from Cellular to Clinical Therapies
Author / Creator:Mitola, Giulia ; Falvo, Paolo ; Bertolini, Francesco
Publisher:Switzerland: MDPI AG
Journal title:Life (Basel, Switzerland), 2021-10, Vol.11 (11), p.1131
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Caloric restriction leads to druggable LSD1-dependent cancer stem cells expansion
Author / Creator:Pallavi, Rani ; Gatti, Elena ; Durfort, Tiphanie ; Stendardo, Massimo ; Ravasio, Roberto ; Leonardi, Tommaso ; Falvo, Paolo ; Duso, Bruno Achutti ; Punzi, Simona ; Xieraili, Aobuli ; Polazzi, Andrea ; Verrelli, Doriana ; Trastulli, Deborah ; Ronzoni, Simona ; Frascolla, Simone ; Perticari, Giulia ; Elgendy, Mohamed ; Varasi, Mario ; Colombo, Emanuela ; Giorgio, Marco ; Lanfrancone, Luisa ; Minucci, Saverio ; Mazzarella, Luca ; Pelicci, Pier Giuseppe
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-01, Vol.15 (1), p.828-18, Article 828
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Parallel single-cell metabolic analysis and extracellular vesicle profiling reveal vulnerabilities with prognostic significance in acute myeloid leukemia
Author / Creator:Forte, Dorian ; Pellegrino, Roberto Maria ; Falvo, Paolo ; Garcia-Gonzalez, Paulina ; Alabed, Husam B. R. ; Maltoni, Filippo ; Lombardi, Davide ; Bruno, Samantha ; Barone, Martina ; Pasini, Federico ; Fabbri, Francesco ; Vannini, Ivan ; Donati, Benedetta ; Cristiano, Gianluca ; Sartor, Chiara ; Ronzoni, Simona ; Ciarrocchi, Alessia ; Buratta, Sandra ; Urbanelli, Lorena ; Emiliani, Carla ; Soverini, Simona ; Catani, Lucia ; Bertolini, Francesco ; Argüello, Rafael José ; Cavo, Michele ; Curti, Antonio
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-12, Vol.15 (1), p.10878-19, Article 10878
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A single-cell transcriptomic landscape of innate and adaptive intratumoral immunity in triple negative breast cancer during chemo- and immunotherapies
Author / Creator:Carpen, Laura ; Falvo, Paolo ; Orecchioni, Stefania ; Mitola, Giulia ; Hillje, Roman ; Mazzara, Saveria ; Mancuso, Patrizia ; Pileri, Stefano ; Raveane, Alessandro ; Bertolini, Francesco
Publisher:London: Nature Publishing Group UK
Journal title:Cell death discovery, 2022-03, Vol.8 (1), p.106-9, Article 106
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HSP and CD279 gene expression as candidate biomarkers in symptomatic LGLL patients
Author / Creator:Talarico, Giovanna ; Franceschini, Andrea ; Raveane, Alessandro ; Falvo, Paolo ; Mazzara, Saveria ; Melle, Federica ; Motta, Giovanna ; Orecchioni, Stefania ; Tenore, Annamaria ; Gregato, Giuliana ; Poletti, Claudia ; Chiarle, Roberto ; Pileri, Stefano ; Mancuso, Patrizia ; Bertolini, Francesco
Publisher:New York: Springer US
Journal title:Discover. Oncology, 2024-12, Vol.15 (1), p.764-19, Article 764
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Cellular and Molecular Players in the Interplay between Adipose Tissue and Breast Cancer
Author / Creator:Reggiani, Francesca ; Falvo, Paolo ; Bertolini, Francesco
Publisher:Switzerland: MDPI
Journal title:International journal of molecular sciences, 2021-01, Vol.22 (3), p.1359
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Tumour-derived PGD2 and NKp30-B7H6 engagement drives an immunosuppressive ILC2-MDSC axis
Author / Creator:Trabanelli, Sara ; Chevalier, Mathieu F. ; Martinez-Usatorre, Amaia ; Gomez-Cadena, Alejandra ; Salomé, Bérengère ; Lecciso, Mariangela ; Salvestrini, Valentina ; Verdeil, Grégory ; Racle, Julien ; Papayannidis, Cristina ; Morita, Hideaki ; Pizzitola, Irene ; Grandclément, Camille ; Bohner, Perrine ; Bruni, Elena ; Girotra, Mukul ; Pallavi, Rani ; Falvo, Paolo ; Leibundgut, Elisabeth Oppliger ; Baerlocher, Gabriela M. ; Carlo-Stella, Carmelo ; Taurino, Daniela ; Santoro, Armando ; Spinelli, Orietta ; Rambaldi, Alessandro ; Giarin, Emanuela ; Basso, Giuseppe ; Tresoldi, Cristina ; Ciceri, Fabio ; Gfeller, David ; Akdis, Cezmi A. ; Mazzarella, Luca ; Minucci, Saverio ; Pelicci, Pier Giuseppe ; Marcenaro, Emanuela ; McKenzie, Andrew N. J. ; Vanhecke, Dominique ; Coukos, George ; Mavilio, Domenico ; Curti, Antonio ; Derré, Laurent ; Jandus, Camilla
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-09, Vol.8 (1), p.593-14, Article 593
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ArticlesPeer ReviewedFull Text
Vinorelbine and Intermittent Cyclophosphamide Sensitize an Aggressive Myc-Driven B-Cell Lymphoma to Anti-PD-1 by an Immunological Memory Effective against Tumor Re-Challenge
Author / Creator:Orecchioni, Stefania ; Falvo, Paolo ; Talarico, Giovanna ; Mitola, Giulia ; Bravetti, Giulia ; Mancuso, Patrizia ; Nicoli, Paola ; Bertolini, Francesco
Publisher:Switzerland: MDPI AG
Journal title:Journal of clinical medicine, 2023-03, Vol.12 (7), p.2535
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Telomeric Repeat-Containing RNAs (TERRA) Decrease in Squamous Cell Carcinoma of the Head and Neck Is Associated with Worsened Clinical Outcome
Author / Creator:Vitelli, Valerio ; Falvo, Paolo ; G. Nergadze, Solomon ; Santagostino, Marco ; Khoriauli, Lela ; Pellanda, Paola ; Bertino, Giulia ; Occhini, Antonio ; Benazzo, Marco ; Morbini, Patrizia ; Paulli, Marco ; Porta, Camillo ; Giulotto, Elena
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2018-01, Vol.19 (1), p.274
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A single-cell transcriptomic landscape of innate and adaptive intratumoral immunity in triple negative breast cancer during chemo- and immunotherapies
Author / Creator:Carpen, Laura ; Falvo, Paolo ; Orecchioni, Stefania ; Mitola, Giulia ; Hillje, Roman ; Mazzara, Saveria ; Mancuso, Patrizia ; Pileri, Stefano ; Raveane, Alessandro ; Bertolini, Francesco
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2021-12
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The breast cancer pro-metastatic phenotype requires concomitant hyper-activation of ECM remodeling and dsRNA-IFN1 signaling in rare clone cells
Author / Creator:Roda, Niccolo ; Cossa, Andrea ; Hillje, Roman ; Tirelli, Andrea ; Ruscitto, Federica ; Cheloni, Stefano ; Priami, Chiara ; Dalmasso, Alberto ; Gambino, Valentina ; Blandano, Giada ; Polazzi, Andrea ; Falvo, Paolo ; Gatti, Elena ; Mazzarella, Luca ; Luzi, Lucilla ; Migliaccio, Enrica ; Pelicci, Pier Giuseppe
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2022-07
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High-fat diet promotes Acute Promyelocytic Leukemia through PPARδ-enhanced self-renewal of preleukemic progenitors
Author / Creator:Mazzarella, Luca ; Falvo, Paolo ; Adinolfi, Marta ; Tini, Giulia ; Gatti, Elena ; Piccioni, Rossana ; Bonetti, Emanuele ; Elena Gavilan Dorronzoro ; Bodini, Margherita ; Gallo, Barbara ; Orecchioni, Stefania ; Duso, Bruno Achutti ; Ronchini, Chiara ; Sanarico, Anna Giulia ; Rani Pallavi ; Roerink, Sophie ; Bertolini, Francesco ; Alcalay, Myriam ; Dellino, Gaetano Ivan ; Pelicci, Pier Giuseppe
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2022-03
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The metabolism of cells regulates their sensitivity to NK cells depending on p53 status

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Metformin sensitizes leukemic cells to cytotoxic lymphocytes by increasing expression of intercellular adhesion molecule-1 (ICAM-1)

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BET inhibitors drive Natural Killer activation in non-small cell lung cancer via BRD4 and SMAD3

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Dual targeting of the DNA damage response pathway and BCL-2 in diffuse large B-cell lymphoma

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New Insight to Overcome Tumor Resistance: An Overview from Cellular to Clinical Therapies

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Caloric restriction leads to druggable LSD1-dependent cancer stem cells expansion

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Parallel single-cell metabolic analysis and extracellular vesicle profiling reveal vulnerabilities with prognostic significance in acute myeloid leukemia

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A single-cell transcriptomic landscape of innate and adaptive intratumoral immunity in triple negative breast cancer during chemo- and immunotherapies

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HSP and CD279 gene expression as candidate biomarkers in symptomatic LGLL patients

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Cellular and Molecular Players in the Interplay between Adipose Tissue and Breast Cancer

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Tumour-derived PGD2 and NKp30-B7H6 engagement drives an immunosuppressive ILC2-MDSC axis

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Vinorelbine and Intermittent Cyclophosphamide Sensitize an Aggressive Myc-Driven B-Cell Lymphoma to Anti-PD-1 by an Immunological Memory Effective against Tumor Re-Challenge

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Telomeric Repeat-Containing RNAs (TERRA) Decrease in Squamous Cell Carcinoma of the Head and Neck Is Associated with Worsened Clinical Outcome

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A single-cell transcriptomic landscape of innate and adaptive intratumoral immunity in triple negative breast cancer during chemo- and immunotherapies

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The breast cancer pro-metastatic phenotype requires concomitant hyper-activation of ECM remodeling and dsRNA-IFN1 signaling in rare clone cells

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High-fat diet promotes Acute Promyelocytic Leukemia through PPARδ-enhanced self-renewal of preleukemic progenitors

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