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Deconstructing sarcomeric structure–function relations in titin-BioID knock-in mice

Deconstructing sarcomeric structure–function relations in titin-BioID knock-in mice

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8f93ea653e124b8e83b6b456aadd7c7e

Deconstructing sarcomeric structure–function relations in titin-BioID knock-in mice

About this item

Full title

Deconstructing sarcomeric structure–function relations in titin-BioID knock-in mice

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2020-06, Vol.11 (1), p.3133-3133, Article 3133

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Proximity proteomics has greatly advanced the analysis of native protein complexes and subcellular structures in culture, but has not been amenable to study development and disease in vivo. Here, we have generated a knock-in mouse with the biotin ligase (BioID) inserted at titin’s Z-disc region to identify protein networks that connect the sarcomer...

Alternative Titles

Full title

Deconstructing sarcomeric structure–function relations in titin-BioID knock-in mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_8f93ea653e124b8e83b6b456aadd7c7e

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8f93ea653e124b8e83b6b456aadd7c7e

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-020-16929-8

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