Deconstructing sarcomeric structure–function relations in titin-BioID knock-in mice
Deconstructing sarcomeric structure–function relations in titin-BioID knock-in mice
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Proximity proteomics has greatly advanced the analysis of native protein complexes and subcellular structures in culture, but has not been amenable to study development and disease in vivo. Here, we have generated a knock-in mouse with the biotin ligase (BioID) inserted at titin’s Z-disc region to identify protein networks that connect the sarcomer...
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Deconstructing sarcomeric structure–function relations in titin-BioID knock-in mice
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TN_cdi_doaj_primary_oai_doaj_org_article_8f93ea653e124b8e83b6b456aadd7c7e
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8f93ea653e124b8e83b6b456aadd7c7e
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-16929-8