BK channels in microglia are required for morphine-induced hyperalgesia
BK channels in microglia are required for morphine-induced hyperalgesia
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Although morphine is a gold standard medication, long-term opioid use is associated with serious side effects, such as morphine-induced hyperalgesia (MIH) and anti-nociceptive tolerance. Microglia-to-neuron signalling is critically involved in pain hypersensitivity. However, molecules that control microglial cellular state under chronic morphine tr...
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BK channels in microglia are required for morphine-induced hyperalgesia
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TN_cdi_doaj_primary_oai_doaj_org_article_8ff4d6db63f3455b927a9ea1c5b258e8
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8ff4d6db63f3455b927a9ea1c5b258e8
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2041-1723
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2041-1723
DOI
10.1038/ncomms11697