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BK channels in microglia are required for morphine-induced hyperalgesia

BK channels in microglia are required for morphine-induced hyperalgesia

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8ff4d6db63f3455b927a9ea1c5b258e8

BK channels in microglia are required for morphine-induced hyperalgesia

About this item

Full title

BK channels in microglia are required for morphine-induced hyperalgesia

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2016-05, Vol.7 (1), p.11697-11697, Article 11697

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Although morphine is a gold standard medication, long-term opioid use is associated with serious side effects, such as morphine-induced hyperalgesia (MIH) and anti-nociceptive tolerance. Microglia-to-neuron signalling is critically involved in pain hypersensitivity. However, molecules that control microglial cellular state under chronic morphine tr...

Alternative Titles

Full title

BK channels in microglia are required for morphine-induced hyperalgesia

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_8ff4d6db63f3455b927a9ea1c5b258e8

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8ff4d6db63f3455b927a9ea1c5b258e8

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/ncomms11697

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