Evasion of immunosurveillance by the upregulation of Siglec15 in bladder cancer
Evasion of immunosurveillance by the upregulation of Siglec15 in bladder cancer
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Author / Creator
Deng, Dingshan , Xiao, Jiatong , Liu, Jinhui , Li, Huihuang , Hu, Minghui , Zhou, Bohan , Liang, Haisu , Fan, Benyi , Chen, Jinbo , Kuang, Xiaogen , Nie, Zhenyu , Hu, Jiao and Zu, Xiongbing
Publisher
England: BMC
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Language
English
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Publisher
England: BMC
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Contents
Immunotherapy resistance in bladder cancer (BLCA) is associated with elevated levels of sialic acid-binding immunoglobulin-like lectin (Siglec15). This protein plays a crucial role in fostering a noninflammatory tumor microenvironment (TME), which is conducive to cancer progression. Our study confirmed that the overexpression of Siglec15 led to a r...
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Full title
Evasion of immunosurveillance by the upregulation of Siglec15 in bladder cancer
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TN_cdi_doaj_primary_oai_doaj_org_article_9011f8b97aa24d08b67eed880c28addd
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9011f8b97aa24d08b67eed880c28addd
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ISSN
1756-8722
E-ISSN
1756-8722
DOI
10.1186/s13045-024-01638-2