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Evasion of immunosurveillance by the upregulation of Siglec15 in bladder cancer

Evasion of immunosurveillance by the upregulation of Siglec15 in bladder cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9011f8b97aa24d08b67eed880c28addd

Evasion of immunosurveillance by the upregulation of Siglec15 in bladder cancer

About this item

Full title

Evasion of immunosurveillance by the upregulation of Siglec15 in bladder cancer

Publisher

England: BMC

Journal title

Journal of hematology and oncology, 2024-11, Vol.17 (1), p.117-5, Article 117

Language

English

Formats

Publication information

Publisher

England: BMC

More information

Scope and Contents

Contents

Immunotherapy resistance in bladder cancer (BLCA) is associated with elevated levels of sialic acid-binding immunoglobulin-like lectin (Siglec15). This protein plays a crucial role in fostering a noninflammatory tumor microenvironment (TME), which is conducive to cancer progression. Our study confirmed that the overexpression of Siglec15 led to a r...

Alternative Titles

Full title

Evasion of immunosurveillance by the upregulation of Siglec15 in bladder cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_9011f8b97aa24d08b67eed880c28addd

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9011f8b97aa24d08b67eed880c28addd

Other Identifiers

ISSN

1756-8722

E-ISSN

1756-8722

DOI

10.1186/s13045-024-01638-2

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