A non-mosaic transchromosomic mouse model of Down syndrome carrying the long arm of human chromosome...
A non-mosaic transchromosomic mouse model of Down syndrome carrying the long arm of human chromosome 21
About this item
Full title
Author / Creator
Kazuki, Yasuhiro , Gao, Feng J , Li, Yicong , Moyer, Anna J , Devenney, Benjamin , Hiramatsu, Kei , Miyagawa-Tomita, Sachiko , Abe, Satoshi , Kazuki, Kanako , Kajitani, Naoyo , Uno, Narumi , Takehara, Shoko , Takiguchi, Masato , Yamakawa, Miho , Hasegawa, Atsushi , Shimizu, Ritsuko , Matsukura, Satoko , Noda, Naohiro , Ogonuki, Narumi , Inoue, Kimiko , Matoba, Shogo , Ogura, Atsuo , Florea, Liliana D , Savonenko, Alena , Xiao, Meifang , Wu, Dan , Batista, Denise AS , Yang, Junhua , Qiu, Zhaozhu , Singh, Nandini , Richtsmeier, Joan T , Takeuchi, Takashi , Oshimura, Mitsuo and Reeves, Roger H
Publisher
England: eLife Sciences Publications Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: eLife Sciences Publications Ltd
Subjects
More information
Scope and Contents
Contents
Animal models of Down syndrome (DS), trisomic for human chromosome 21 (HSA21) genes or orthologs, provide insights into better understanding and treatment options. The only existing transchromosomic (Tc) mouse DS model, Tc1, carries a HSA21 with over 50 protein coding genes (PCGs) disrupted. Tc1 is mosaic, compromising interpretation of results. He...
Alternative Titles
Full title
A non-mosaic transchromosomic mouse model of Down syndrome carrying the long arm of human chromosome 21
Authors, Artists and Contributors
Author / Creator
Gao, Feng J
Li, Yicong
Moyer, Anna J
Devenney, Benjamin
Hiramatsu, Kei
Miyagawa-Tomita, Sachiko
Abe, Satoshi
Kazuki, Kanako
Kajitani, Naoyo
Uno, Narumi
Takehara, Shoko
Takiguchi, Masato
Yamakawa, Miho
Hasegawa, Atsushi
Shimizu, Ritsuko
Matsukura, Satoko
Noda, Naohiro
Ogonuki, Narumi
Inoue, Kimiko
Matoba, Shogo
Ogura, Atsuo
Florea, Liliana D
Savonenko, Alena
Xiao, Meifang
Wu, Dan
Batista, Denise AS
Yang, Junhua
Qiu, Zhaozhu
Singh, Nandini
Richtsmeier, Joan T
Takeuchi, Takashi
Oshimura, Mitsuo
Reeves, Roger H
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_902bee1fcc954ec09607d3e505b90a1b
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_902bee1fcc954ec09607d3e505b90a1b
Other Identifiers
ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.56223
