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ArticlesPeer ReviewedFull Text
Allogeneic transplantation of iPS cell-derived cardiomyocytes regenerates primate hearts
Author / Creator:Shiba, Yuji ; Gomibuchi, Toshihito ; Seto, Tatsuichiro ; Wada, Yuko ; Ichimura, Hajime ; Tanaka, Yuki ; Ogasawara, Tatsuki ; Okada, Kenji ; Shiba, Naoko ; Sakamoto, Kengo ; Ido, Daisuke ; Shiina, Takashi ; Ohkura, Masamichi ; Nakai, Junichi ; Uno, Narumi ; Kazuki, Yasuhiro ; Oshimura, Mitsuo ; Minami, Itsunari ; Ikeda, Uichi
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2016-10, Vol.538 (7625), p.388-391
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Human Artificial Chromosomes for Gene Delivery and the Development of Animal Models
Author / Creator:Kazuki, Yasuhiro ; Oshimura, Mitsuo
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy, 2011-09, Vol.19 (9), p.1591-1601
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Dynamics of epigenetic regulation at the single-cell level
Author / Creator:Bintu, Lacramioara ; Yong, John ; Antebi, Yaron E. ; McCue, Kayla ; Kazuki, Yasuhiro ; Uno, Narumi ; Oshimura, Mitsuo ; Elowitz, Michael B.
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2016-02, Vol.351 (6274), p.720-724
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Highly Efficient Transfer of Chromosomes to a Broad Range of Target Cells Using Chinese Hamster Ovary Cells Expressing Murine Leukemia Virus-Derived Envelope Proteins
Author / Creator:Suzuki, Teruhiko ; Kazuki, Yasuhiro ; Oshimura, Mitsuo ; Hara, Takahiko
Publisher:United States: Public Library of Science
Journal title:PloS one, 2016-06, Vol.11 (6), p.e0157187-e0157187
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Efficient human-like antibody repertoire and hybridoma production in trans-chromosomic mice carrying megabase-sized human immunoglobulin loci
Author / Creator:Satofuka, Hiroyuki ; Abe, Satoshi ; Moriwaki, Takashi ; Okada, Akane ; Kazuki, Kanako ; Tanaka, Hiroshi ; Yamazaki, Kyotaro ; Hichiwa, Genki ; Morimoto, Kayoko ; Takayama, Haruka ; Nakayama, Yuji ; Hatano, Shinya ; Yada, Yutaro ; Murakami, Yasufumi ; Baba, Yoshihiro ; Oshimura, Mitsuo ; Tomizuka, Kazuma ; Kazuki, Yasuhiro
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-04, Vol.13 (1), p.1841-1841, Article 1841
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Blastocyst complementation using Prdm14-deficient rats enables efficient germline transmission and generation of functional mouse spermatids in rats
Author / Creator:Kobayashi, Toshihiro ; Goto, Teppei ; Oikawa, Mami ; Sanbo, Makoto ; Yoshida, Fumika ; Terada, Reiko ; Niizeki, Naoko ; Kajitani, Naoyo ; Kazuki, Kanako ; Kazuki, Yasuhiro ; Hochi, Shinichi ; Nakauchi, Hiromitsu ; Surani, M. Azim ; Hirabayashi, Masumi
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-02, Vol.12 (1), p.1328-1328, Article 1328
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Aging of spermatogonial stem cells by Jnk-mediated glycolysis activation
Author / Creator:Kanatsu-Shinohara, Mito ; Yamamoto, Takuya ; Toh, Hidehiro ; Kazuki, Yasuhiro ; Kazuki, Kanako ; Imoto, Junichi ; Ikeo, Kazuho ; Oshima, Motohiko ; Shirahige, Katsuhiko ; Iwama, Atsushi ; Nabeshima, Yoichi ; Sasaki, Hiroyuki ; Shinohara, Takashi
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2019-08, Vol.116 (33), p.16404-16409
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A Novel System for Simultaneous or Sequential Integration of Multiple Gene-Loading Vectors into a Defined Site of a Human Artificial Chromosome
Author / Creator:Suzuki, Teruhiko ; Kazuki, Yasuhiro ; Oshimura, Mitsuo ; Hara, Takahiko
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014-10, Vol.9 (10), p.e110404-e110404
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Titin fragment is a sensitive biomarker in Duchenne muscular dystrophy model mice carrying full-length human dystrophin gene on human artificial chromosome
Author / Creator:Hiramuki, Yosuke ; Hosokawa, Miwa ; Osawa, Kayo ; Shirakawa, Taku ; Watanabe, Yasuhiro ; Hanajima, Ritsuko ; Kugoh, Hiroyuki ; Awano, Hiroyuki ; Matsuo, Masafumi ; Kazuki, Yasuhiro
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2025-01, Vol.15 (1), p.1778-9, Article 1778
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Construction of stable mouse artificial chromosome from native mouse chromosome 10 for generation of transchromosomic mice
Author / Creator:Abe, Satoshi ; Honma, Kazuhisa ; Okada, Akane ; Kazuki, Kanako ; Tanaka, Hiroshi ; Endo, Takeshi ; Morimoto, Kayoko ; Moriwaki, Takashi ; Hamamichi, Shusei ; Nakayama, Yuji ; Suzuki, Teruhiko ; Takehara, Shoko ; Oshimura, Mitsuo ; Kazuki, Yasuhiro
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2021-10, Vol.11 (1), p.20050-12, Article 20050
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A pathway from chromosome transfer to engineering resulting in human and mouse artificial chromosomes for a variety of applications to bio-medical challenges
Author / Creator:Oshimura, Mitsuo ; Uno, Narumi ; Kazuki, Yasuhiro ; Katoh, Motonobu ; Inoue, Toshiaki
Publisher:Dordrecht: Springer Netherlands
Journal title:Chromosome research, 2015-02, Vol.23 (1), p.111-133
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Pluripotent stem cell model of early hematopoiesis in Down syndrome reveals quantitative effects of short-form GATA1 protein on lineage specification
Author / Creator:Matsuo, Shiori ; Nishinaka-Arai, Yoko ; Kazuki, Yasuhiro ; Oshimura, Mitsuo ; Nakahata, Tatsutoshi ; Niwa, Akira ; Saito, Megumu K.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2021-03, Vol.16 (3), p.e0247595-e0247595
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Hypermetabolism in mice carrying a near-complete human chromosome 21
Author / Creator:Sarver, Dylan C ; Xu, Cheng ; Rodriguez, Susana ; Aja, Susan ; Jaffe, Andrew E ; Gao, Feng J ; Delannoy, Michael ; Periasamy, Muthu ; Kazuki, Yasuhiro ; Oshimura, Mitsuo ; Reeves, Roger H ; Wong, G William
Publisher:England: eLife Sciences Publications Ltd
Journal title:eLife, 2023-05, Vol.12
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ArticlesPeer ReviewedFull Text
Bioluminescence Measurement of Time-Dependent Dynamic Changes of CYP-Mediated Cytotoxicity in CYP-Expressing Luminescent HepG2 Cells
Author / Creator:Iwado, Satoru ; Abe, Satoshi ; Oshimura, Mitsuo ; Kazuki, Yasuhiro ; Nakajima, Yoshihiro
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2021-03, Vol.22 (6), p.2843
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Combinations of chromosome transfer and genome editing for the development of cell/animal models of human disease and humanized animal models
Author / Creator:Uno, Narumi ; Abe, Satoshi ; Oshimura, Mitsuo ; Kazuki, Yasuhiro
Publisher:England: Nature Publishing Group
Journal title:Journal of human genetics, 2018-02, Vol.63 (2), p.145-156
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Panel of human cell lines with human/mouse artificial chromosomes
Author / Creator:Uno, Narumi ; Takata, Shuta ; Komoto, Shinya ; Miyamoto, Hitomaru ; Nakayama, Yuji ; Osaki, Mitsuhiko ; Mayuzumi, Ryota ; Miyazaki, Natsumi ; Hando, Chiaki ; Abe, Satoshi ; Sakuma, Tetsushi ; Yamamoto, Takashi ; Suzuki, Teruhiko ; Nakajima, Yoshihiro ; Oshimura, Mitsuo ; Tomizuka, Kazuma ; Kazuki, Yasuhiro
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2022-02, Vol.12 (1), p.3009-3009, Article 3009
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A non-mosaic transchromosomic mouse model of Down syndrome carrying the long arm of human chromosome 21
Author / Creator:Kazuki, Yasuhiro ; Gao, Feng J ; Li, Yicong ; Moyer, Anna J ; Devenney, Benjamin ; Hiramatsu, Kei ; Miyagawa-Tomita, Sachiko ; Abe, Satoshi ; Kazuki, Kanako ; Kajitani, Naoyo ; Uno, Narumi ; Takehara, Shoko ; Takiguchi, Masato ; Yamakawa, Miho ; Hasegawa, Atsushi ; Shimizu, Ritsuko ; Matsukura, Satoko ; Noda, Naohiro ; Ogonuki, Narumi ; Inoue, Kimiko ; Matoba, Shogo ; Ogura, Atsuo ; Florea, Liliana D ; Savonenko, Alena ; Xiao, Meifang ; Wu, Dan ; Batista, Denise AS ; Yang, Junhua ; Qiu, Zhaozhu ; Singh, Nandini ; Richtsmeier, Joan T ; Takeuchi, Takashi ; Oshimura, Mitsuo ; Reeves, Roger H
Publisher:England: eLife Sciences Publications Ltd
Journal title:eLife, 2020-06, Vol.9
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Rejuvenation of human mesenchymal stem cells using a nonintegrative and conditionally removable Sendai virus vector
Author / Creator:Oshimura, Mitsuo ; Tabata, Toshiaki ; Uno, Narumi ; Takata, Shuta ; Hichiwa, Genki ; Kanazawa, Iori ; Endo, Takeshi ; Honma, Kazuhisa ; Wang, Yayan ; Kazuki, Kanako ; Tu, Haochen ; Iida, Yuichi ; Abe, Satoshi ; Kazuki, Yasuhiro
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2024-10, Vol.14 (1), p.23623-11, Article 23623
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Complete Genetic Correction of iPS Cells From Duchenne Muscular Dystrophy
Author / Creator:Kazuki, Yasuhiro ; Hiratsuka, Masaharu ; Takiguchi, Masato ; Osaki, Mitsuhiko ; Kajitani, Naoyo ; Hoshiya, Hidetoshi ; Hiramatsu, Kei ; Yoshino, Toko ; Kazuki, Kanako ; Ishihara, Chie ; Takehara, Shoko ; Higaki, Katsumi ; Nakagawa, Masato ; Takahashi, Kazutoshi ; Yamanaka, Shinya ; Oshimura, Mitsuo
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy, 2010-02, Vol.18 (2), p.386-393
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Developing a workflow for the isolation of hybridoma cells producing fully human antigen-specific antibodies using a surface IgG detection method
Author / Creator:Satofuka, Hiroyuki ; Wang, Yayan ; Tanaka, Hiroshi ; Hiramatsu, Kei ; Morimoto, Kayoko ; Takayama, Haruka ; Tu, Haochen ; Qiao, Yu ; Ito, Satoru ; Gao, Xu ; Oshimura, Mitsuo ; Kazuki, Yasuhiro
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2024-10, Vol.14 (1), p.23138-11, Article 23138
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Showing 1 to 20 of 76 results

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Allogeneic transplantation of iPS cell-derived cardiomyocytes regenerates primate hearts

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Human Artificial Chromosomes for Gene Delivery and the Development of Animal Models

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Dynamics of epigenetic regulation at the single-cell level

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Highly Efficient Transfer of Chromosomes to a Broad Range of Target Cells Using Chinese Hamster Ovary Cells Expressing Murine Leukemia Virus-Derived Envelope Proteins

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Efficient human-like antibody repertoire and hybridoma production in trans-chromosomic mice carrying megabase-sized human immunoglobulin loci

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Blastocyst complementation using Prdm14-deficient rats enables efficient germline transmission and generation of functional mouse spermatids in rats

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Aging of spermatogonial stem cells by Jnk-mediated glycolysis activation

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A Novel System for Simultaneous or Sequential Integration of Multiple Gene-Loading Vectors into a Defined Site of a Human Artificial Chromosome

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Titin fragment is a sensitive biomarker in Duchenne muscular dystrophy model mice carrying full-length human dystrophin gene on human artificial chromosome

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Construction of stable mouse artificial chromosome from native mouse chromosome 10 for generation of transchromosomic mice

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A pathway from chromosome transfer to engineering resulting in human and mouse artificial chromosomes for a variety of applications to bio-medical challenges

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Pluripotent stem cell model of early hematopoiesis in Down syndrome reveals quantitative effects of short-form GATA1 protein on lineage specification

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Hypermetabolism in mice carrying a near-complete human chromosome 21

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Bioluminescence Measurement of Time-Dependent Dynamic Changes of CYP-Mediated Cytotoxicity in CYP-Expressing Luminescent HepG2 Cells

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Combinations of chromosome transfer and genome editing for the development of cell/animal models of human disease and humanized animal models

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Panel of human cell lines with human/mouse artificial chromosomes

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A non-mosaic transchromosomic mouse model of Down syndrome carrying the long arm of human chromosome 21

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Rejuvenation of human mesenchymal stem cells using a nonintegrative and conditionally removable Sendai virus vector

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Complete Genetic Correction of iPS Cells From Duchenne Muscular Dystrophy

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Developing a workflow for the isolation of hybridoma cells producing fully human antigen-specific antibodies using a surface IgG detection method

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