The ER membrane-anchored ubiquitin ligase Hrd1 is a positive regulator of T-cell immunity
The ER membrane-anchored ubiquitin ligase Hrd1 is a positive regulator of T-cell immunity
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Identification of positive regulators of T-cell immunity induced during autoimmune diseases is critical for developing novel therapies. The endoplasmic reticulum resident ubiquitin ligase Hrd1 has recently emerged as a critical regulator of dendritic cell antigen presentation, but its role in T-cell immunity is unknown. Here we show that genetic de...
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The ER membrane-anchored ubiquitin ligase Hrd1 is a positive regulator of T-cell immunity
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TN_cdi_doaj_primary_oai_doaj_org_article_902e7181d4964ee6a11b99d4dc6b4007
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_902e7181d4964ee6a11b99d4dc6b4007
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms12073
