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CK1epsilon is required for breast cancers dependent on beta-catenin activity

CK1epsilon is required for breast cancers dependent on beta-catenin activity

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_90e571fb5751489c86befcf74ee130b8

CK1epsilon is required for breast cancers dependent on beta-catenin activity

About this item

Full title

CK1epsilon is required for breast cancers dependent on beta-catenin activity

Publisher

United States: Public Library of Science (PLoS)

Journal title

PloS one, 2010-02, Vol.5 (2), p.e8979

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science (PLoS)

More information

Scope and Contents

Contents

Aberrant beta-catenin signaling plays a key role in several cancer types, notably colon, liver and breast cancer. However approaches to modulate beta-catenin activity for therapeutic purposes have proven elusive to date.
To uncover genetic dependencies in breast cancer cells that harbor active beta-catenin signaling, we performed RNAi-based loss...

Alternative Titles

Full title

CK1epsilon is required for breast cancers dependent on beta-catenin activity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_90e571fb5751489c86befcf74ee130b8

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_90e571fb5751489c86befcf74ee130b8

Other Identifiers

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0008979

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