CK1epsilon is required for breast cancers dependent on beta-catenin activity
CK1epsilon is required for breast cancers dependent on beta-catenin activity
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United States: Public Library of Science (PLoS)
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Language
English
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Publisher
United States: Public Library of Science (PLoS)
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Contents
Aberrant beta-catenin signaling plays a key role in several cancer types, notably colon, liver and breast cancer. However approaches to modulate beta-catenin activity for therapeutic purposes have proven elusive to date.
To uncover genetic dependencies in breast cancer cells that harbor active beta-catenin signaling, we performed RNAi-based loss...
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Full title
CK1epsilon is required for breast cancers dependent on beta-catenin activity
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TN_cdi_doaj_primary_oai_doaj_org_article_90e571fb5751489c86befcf74ee130b8
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_90e571fb5751489c86befcf74ee130b8
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E-ISSN
1932-6203
DOI
10.1371/journal.pone.0008979
