Inhibiting BDNF/TrkB.T1 receptor improves resiniferatoxin-induced postherpetic neuralgia through dec...
Inhibiting BDNF/TrkB.T1 receptor improves resiniferatoxin-induced postherpetic neuralgia through decreasing ASIC3 signaling in dorsal root ganglia
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Author / Creator
Wei, Xiang , Wang, Lina , Hua, Jie , Jin, Xiao-Hong , Ji, Fuhai , Peng, Ke , Zhou, Bin , Yang, Jianping and Meng, Xiao-Wen
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Postherpetic neuralgia (PHN) is a devastating complication after varicella-zoster virus infection. Brain-derived neurotrophic factor (BDNF) has been shown to participate in the pathogenesis of PHN. A truncated isoform of the tropomyosin receptor kinase B (TrkB) receptor TrkB.T1, as a high-affinity receptor of BDNF, is upregulated in multiple nervou...
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Full title
Inhibiting BDNF/TrkB.T1 receptor improves resiniferatoxin-induced postherpetic neuralgia through decreasing ASIC3 signaling in dorsal root ganglia
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TN_cdi_doaj_primary_oai_doaj_org_article_91300c47ee354898adbaee28d36f7072
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_91300c47ee354898adbaee28d36f7072
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ISSN
1742-2094
E-ISSN
1742-2094
DOI
10.1186/s12974-021-02148-5