Clearing Extracellular Alpha-Synuclein from Cerebrospinal Fluid: A New Therapeutic Strategy in Parki...
Clearing Extracellular Alpha-Synuclein from Cerebrospinal Fluid: A New Therapeutic Strategy in Parkinson's Disease
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Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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This concept article aims to show the rationale of targeting extracellular α-Synuclein (α-Syn) from cerebrospinal fluid (CSF) as a new strategy to remove this protein from the brain in Parkinson's disease (PD). Misfolding and intracellular aggregation of α-synuclein into Lewy bodies are thought to be crucial in the pathogenesis of PD. Recent resear...
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Full title
Clearing Extracellular Alpha-Synuclein from Cerebrospinal Fluid: A New Therapeutic Strategy in Parkinson's Disease
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TN_cdi_doaj_primary_oai_doaj_org_article_91a88a9cda7042938e55c691993bb275
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_91a88a9cda7042938e55c691993bb275
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ISSN
2076-3425
E-ISSN
2076-3425
DOI
10.3390/brainsci8040052
