Ginsenoside Re Inhibits ROS/ASK-1 Dependent Mitochondrial Apoptosis Pathway and Activation of Nrf2-A...
Ginsenoside Re Inhibits ROS/ASK-1 Dependent Mitochondrial Apoptosis Pathway and Activation of Nrf2-Antioxidant Response in Beta-Amyloid-Challenged SH-SY5Y Cells
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Author / Creator
Liu, Meichen , Bai, Xueyuan , Yu, Shiting , Zhao, Wenxue , Qiao, Juhui , Liu, Ying , Zhao, Daqing , Wang, Jiawen and Wang, Siming
Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Accumulation of amyloid-β (Aβ), which results in the formation of senile plaques that cause oxidative damage and neuronal cell death, has been accepted as the major pathological mechanism of Alzheimer's disease (AD). Hence, inhibition of Aβ-induced oxidative damage and neuronal cell apoptosis represents the effective strategies in combating AD. Gin...
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Full title
Ginsenoside Re Inhibits ROS/ASK-1 Dependent Mitochondrial Apoptosis Pathway and Activation of Nrf2-Antioxidant Response in Beta-Amyloid-Challenged SH-SY5Y Cells
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TN_cdi_doaj_primary_oai_doaj_org_article_91c284f4acbd413ab7eb31a8b27941de
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_91c284f4acbd413ab7eb31a8b27941de
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ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules24152687