Amyloid-β (Aβ) immunotherapy induced microhemorrhages are associated with activated perivascular mac...
Amyloid-β (Aβ) immunotherapy induced microhemorrhages are associated with activated perivascular macrophages and peripheral monocyte recruitment in Alzheimer’s disease mice
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London: BioMed Central
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English
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London: BioMed Central
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BackgroundAmyloid-related imaging abnormalities (ARIA) have been identified as the most common and serious adverse events resulting from pathological changes in the cerebral vasculature during several recent anti-amyloid-β (Aβ) immunotherapy trials. However, the precise cellular and molecular mechanisms underlying how amyloid immunotherapy enhances...
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Amyloid-β (Aβ) immunotherapy induced microhemorrhages are associated with activated perivascular macrophages and peripheral monocyte recruitment in Alzheimer’s disease mice
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TN_cdi_doaj_primary_oai_doaj_org_article_92504fa84574440fa1b3fbeddb47ce41
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_92504fa84574440fa1b3fbeddb47ce41
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1750-1326
E-ISSN
1750-1326
DOI
10.1186/s13024-023-00649-w