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Amyloid-β (Aβ) immunotherapy induced microhemorrhages are associated with activated perivascular mac...

Amyloid-β (Aβ) immunotherapy induced microhemorrhages are associated with activated perivascular mac...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_92504fa84574440fa1b3fbeddb47ce41

Amyloid-β (Aβ) immunotherapy induced microhemorrhages are associated with activated perivascular macrophages and peripheral monocyte recruitment in Alzheimer’s disease mice

About this item

Full title

Amyloid-β (Aβ) immunotherapy induced microhemorrhages are associated with activated perivascular macrophages and peripheral monocyte recruitment in Alzheimer’s disease mice

Publisher

London: BioMed Central

Journal title

Molecular neurodegeneration, 2023-08, Vol.18 (1), p.1-59, Article 59

Language

English

Formats

Publication information

Publisher

London: BioMed Central

More information

Scope and Contents

Contents

BackgroundAmyloid-related imaging abnormalities (ARIA) have been identified as the most common and serious adverse events resulting from pathological changes in the cerebral vasculature during several recent anti-amyloid-β (Aβ) immunotherapy trials. However, the precise cellular and molecular mechanisms underlying how amyloid immunotherapy enhances...

Alternative Titles

Full title

Amyloid-β (Aβ) immunotherapy induced microhemorrhages are associated with activated perivascular macrophages and peripheral monocyte recruitment in Alzheimer’s disease mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_92504fa84574440fa1b3fbeddb47ce41

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_92504fa84574440fa1b3fbeddb47ce41

Other Identifiers

ISSN

1750-1326

E-ISSN

1750-1326

DOI

10.1186/s13024-023-00649-w

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