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Signaling of High Mobility Group Box 1 (HMGB1) through Toll-like Receptor 4 in Macrophages Requires...

Signaling of High Mobility Group Box 1 (HMGB1) through Toll-like Receptor 4 in Macrophages Requires...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_92b9e541abc146bfb6c6222a91fe8dca

Signaling of High Mobility Group Box 1 (HMGB1) through Toll-like Receptor 4 in Macrophages Requires CD14

About this item

Full title

Signaling of High Mobility Group Box 1 (HMGB1) through Toll-like Receptor 4 in Macrophages Requires CD14

Publisher

England: BioMed Central

Journal title

Molecular medicine (Cambridge, Mass.), 2013-01, Vol.19 (1), p.88-98

Language

English

Formats

Publication information

Publisher

England: BioMed Central

More information

Scope and Contents

Contents

High mobility group box 1 (HMGB1) is a DNA-binding protein that possesses cytokinelike, proinflammatory properties when released extracellularly in the C23–C45 disulfide form. HMGB1 also plays a key role as a mediator of acute and chronic inflammation in models of sterile injury. Although HMGB1 interacts with multiple pattern recognition receptors...

Alternative Titles

Full title

Signaling of High Mobility Group Box 1 (HMGB1) through Toll-like Receptor 4 in Macrophages Requires CD14

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_92b9e541abc146bfb6c6222a91fe8dca

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_92b9e541abc146bfb6c6222a91fe8dca

Other Identifiers

ISSN

1076-1551

E-ISSN

1528-3658

DOI

10.2119/molmed.2012.00306

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